645419-13-2 Usage
Uses
Used in Pharmaceutical Research:
1-(6'-Aminospiro[cyclopropane-1,3'-indolin]-1'-yl)ethanone is utilized as a building block in the synthesis of drug candidates, leveraging its unique spiropiperidine structure to contribute to the development of novel therapeutic agents.
Used in Medicinal Chemistry:
As a chemical probe, 1-(6'-Aminospiro[cyclopropane-1,3'-indolin]-1'-yl)ethanone aids in the study of biological processes, providing insights into molecular interactions and mechanisms that can inform the design of new drugs and therapeutic strategies.
Used in Drug Discovery:
In the drug discovery process, 1-(6'-Aminospiro[cyclopropane-1,3'-indolin]-1'-yl)ethanone serves as a valuable tool for screening and optimization, enabling researchers to identify and refine potential drug candidates with improved efficacy and selectivity.
Further studies are essential to fully explore the potential of 1-(6'-Aminospiro[cyclopropane-1,3'-indolin]-1'-yl)ethanone across various applications, including but not limited to the pharmaceutical industry, where its unique properties may lead to breakthroughs in drug development and treatment of various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 645419-13-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,5,4,1 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 645419-13:
(8*6)+(7*4)+(6*5)+(5*4)+(4*1)+(3*9)+(2*1)+(1*3)=162
162 % 10 = 2
So 645419-13-2 is a valid CAS Registry Number.
645419-13-2Relevant academic research and scientific papers
MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
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, (2012/12/14)
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES
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, (2012/04/23)
The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.
SUBSTITUTED ANTHRANILIC AMIDE DERIVATIVES AND METHODS OF USE
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Page 170-171, (2010/02/06)
Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
