64563-49-1

Upstream product

• 596-43-0 bromo-triphenyl-methane 
• 76-83-5 trityl chloride 
• 233759-67-6 4-(2-trityloxy-ethyl)-[1,3]dioxolan-2-one 
• 4779-04-8 1-trityloxybut-3-ene 

Downstream Products

• 233759-68-7 C₅₉H₉₂O₃ 

Relevant academic research and scientific papers

An efficient and selective method for hydrolysis of acetonides

Acetonide was selectively and efficiently cleaved with cerium (III) chloride heptahydrate and oxalic acid in acetonitrile. This method was found to be of good functionalities compatibility with such acid sensitive groups as Tr, PMB, TBDMS, TBDPS, OAc, OBz, OTs, OTf.

Synthesis of diether-linked cationic lipids for gene delivery

Quaternary ammonium lipids 1b-d, with diether linkages between hydrocarbon chains and butane or hexane backbone, were synthesized for cationic liposome-mediated gene delivery. The synthetic strategy of using C- 4 or C-6 synthon permits the achievement of the variation of the hydrophobic domain as well as changes of space between the quaternary ammonium head and the hydrophobic domain in the diether-linked cationic lipids.