64573-32-6Relevant academic research and scientific papers
Synthesis and biological activity of novel benzoazoles, benzoazines and other analogs functionalized by 2,4-dihydroxyphenyl moiety
Matysiak, Joanna,Skrzypek, Alicja,G?aszcz, Urszula,Matwijczuk, Arkadiusz,Senczyna, Bogdan,Wietrzyk, Joanna,Krajewska-Ku?ak, El?bieta,Niewiadomy, Andrzej
, p. 6169 - 6182 (2018)
Novel benzoazoles, benzoazines, benzothiazoles, benzothiazines and other related compounds possessing a 2,4-dihydroxyphenyl moiety were prepared. The compounds were obtained by the reaction of sulfinylbis[(2,4-dihydroxyphenyl)methanethione]s with the appropriate heterocyclic amines or hydrazines. The structures of the compounds were proved by IR, 1H NMR, and mass spectral data. Human cancer lines, Candida species and phytopathogenic fungi were used for the evaluation of biological potency of compounds. Additionally, drug-like properties were estimated in silico.
