64598-35-2Relevant academic research and scientific papers
Simple and effective route for synthesis of parvaquone, an antiprotozoal drug
Patil, Pravin C.,Akamanchi, Krishnacharya G.
, p. 58214 - 58216 (2015/02/19)
Parvaquone, an antiprotozoal agent against Theileria parva, was synthesized in 33.8% overall yield by using cheap, commercially available raw materials. A key intermediate, 2-cyclohexyl-1-naphthol, was synthesized in 86% yield by cyclohexylation of 1-naphthol and further converted into parvaquone in good yield through reaction sequences such as oxidation and epoxidation followed by isomerization.
