64614-47-7

Usage

Uses

Used in Chemical Synthesis:
2-CHLORO-5-(PYRROLIDIN-1-YLCARBONYL)PYRIDINE is used as a building block in the synthesis of organic compounds for various applications, such as pharmaceuticals, agrochemicals, and materials science.
Used in Pharmaceutical Drug Development:
2-CHLORO-5-(PYRROLIDIN-1-YLCARBONYL)PYRIDINE is used as a key intermediate in the development of pharmaceutical drugs, contributing to the creation of novel therapeutic agents.
Used in Medicinal Chemistry Research:
2-CHLORO-5-(PYRROLIDIN-1-YLCARBONYL)PYRIDINE is used as a research tool in medicinal chemistry to explore its potential biological activity and its role in the discovery of new drugs.
Used in Chemical and Pharmaceutical Industries:
2-CHLORO-5-(PYRROLIDIN-1-YLCARBONYL)PYRIDINE is used as a chemical intermediate for the production of various compounds and drugs in the chemical and pharmaceutical industries.

InChI:InChI=1/C10H11ClN2O/c11-9-4-3-8(7-12-9)10(14)13-5-1-2-6-13/h3-4,7H,1-2,5-6H2

Upstream product

• 123-75-1 pyrrolidine 
• 5326-23-8 6-Chloro-3-pyridinecarboxylic acid 
• 58757-38-3 6-Chloronicotinoyl chloride 

Downstream Products

• 749913-39-1 4-phenyl-1-[5-(1-pyrrolidinylcarbonyl)-2-pyridinyl]-4-piperidinecarboxylic acid, methyl ester 
• 749913-34-6 1-[[6-(4-cyano-4-phenyl-1-piperidinyl)-3-pyridinyl]carbonyl]pyrrolidine hydrochloride 

Relevant academic research and scientific papers

Piperidyl amides as novel, potent and orally active mGlu5 receptor antagonists with anxiolytic-like activity

High throughput screening led to the identification of nicotinamide derivative 2 as a structurally novel mGluR5 antagonist. Optimization of the modular scaffold led to the discovery of 16m, a compound with high affinity for mGluR5 and excellent selectivit

INDENYL DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF NEUROLOGICAL DISORDERS

The present invention relates to novel indenyl derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.

NOVEL COMPOUNDS

The present invention relates to pyridine derivatives or formula (I) where A is a 4-, 5- or 6-membered saturated ring; R1, R2 and R3 are organic groups as specified in the application. Processes for their preparation, phar

NOVEL COMPOUNDS

The invention relates to pyridine derivatives of formula (I) where the variables are defined in the specification.Processes for the preparation of these compounds together with pharmaceutical compositions containing them and their use in therapy in particular in the modulation of autoimmune disease is also described.

NOVEL COMPOUNDS

The invention relates to pyridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

PIPERAZINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISEASES

The present invention relates to novel piperidine carbonyl piperazine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.