64621-41-6

Usage

Family

Xylene family

Composition

Two 4-formylphenoxy groups connected by a 1,3-xylene backbone

Applications

Production of polymers and resins
Synthesis of dyes and pharmaceuticals
Potential use in organic electronic devices

Electronic and optical properties

Unique, which makes it suitable for organic electronic devices

Toxicity

Low toxicity, but proper handling and safety precautions should be observed

Safety

Handle with care and follow safety guidelines when working with this chemical compound

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 623-25-6 p-Xylylene dichloride 
• 623-24-5 1,4-bis(bromomethyl)benzene 
• 58765-11-0 4-hydroxybenzaldehyde potassium salt 

Downstream Products

• 170651-96-4 [1,4-phenylene-bis(methyleneoxy-4,1-phenylene)]dimethanol 
• 1165762-28-6 4-(4-(4-((4-(6-(3-nitrophenyl)-4-phenyl-1,3-diazabicyclo[3.1.0]hex-3-en-2-yl)phenoxy)methyl)benzyloxy)phenyl)-6-(3-nitrophenyl)-2-phenyl-3,5-diazabicyclo[3.1.0]hex-2-ene 
• 1165762-26-4 4-(4-(4-((4-(6-(4-nitrophenyl)-4-phenyl-1,3-diazabicyclo[3.1.0]hex-3-en-2-yl)phenoxy)methyl)benzyloxy)phenyl)-6-(4-nitrophenyl)-2-phenyl-3,5-diazabicyclo[3.1.0]hex-2-ene 

Relevant academic research and scientific papers

Poly(azomethine-epoxy-ether) containing phenyl and etoxy moieties: synthesis, characterization and fluorescence property

The design and synthesis of poly(azomethine-epoxy-ether) (PAZ-EP) containing epoxide moiety was described. The purpose of the research was the improvement of poly(azomethine-ether) containing epoxide by introduction of Schiff base moiety. PAZ-EP was synthesized using epichlorohydrin (EP). The structure of the Schiff base (SB) and PAZ-EP were verified by FT-IR, 1H-NMR, 13C-NMR and UV–Vis spectroscopic analyses. Further characterization was employed using photophysical, electrochemical and fluorescence (PL) measurements. Application of TGA and differential scanning calorimetry analyses revealed thermal stability and thus propose a thermal processibility, which makes them potential materials for many contemporary practices. The number of average molecular weight of polymer with a polydispersity index of 1.14 was found to be 6750?Da using a gel permeation chromatography instrument. The highest occupied–lowest unoccupied energy levels and electrochemical (Eg′) band gap values of PAZ-EP were determined by cyclic voltammetry (CV) measurement. Scanning electron microscopy (SEM) images were illustrated at different magnifications to study the morphologic property of PAZ-EP.

C2-Symmetric chiral diamine ligands for enantiomeric recognition of amino acid esters and mandelic acid by proton nmr titration method

Two novel C2 -symmetric chiral diamines containing α-phenylethyl and α-(1-naphthyl)ethyl chiral subunits were prepared with quantitative yields. Enantiomeric recognition properties of these simple structured diamine ligands towards D- and L-amino acid est

Green synthesis of novel bis(hexahydro-1H-xanthene-1,8(2H)-diones) employing p-toluenesulfonic acid (p-TSA) as a solid acid catalyst

Green synthesis of novel bis(hexahydro-1H-xanthene-1,8(2H)-diones) which are linked to aliphatic or aromatic spacers via ether or ester linkages were performed in good to excellent yields by the reaction of 5,5-dimethyl-1,3-cyclohexanedione with the appropriate bis-aldehydes using p-TSA as an organic acid solid catalyst. The reaction of the bis-aldehydes with barbituric acid or 1,3-dimethylbarbituric acid instead of 5,5-dimethyl-1,3-cyclohexanedione afforded the corresponding Knoevenagel condensation adducts in good yield.

Multicomponent synthesis of new bis(pyranopyrazoles) and their antimicrobial–antioxidant evaluations

One-pot, three-component reactions were utilized to obtain a series of new symmetrical bis(pyranopyrazoles) built around six rigid linkers in good yields and in the short durations under normal conditions. The structures of the prepared compounds were confirmed using their IR, 1H-NMR, 13C-NMR and ESI-MS spectral parameters. The bis(pyranopyrazoles) 3b and 3f exhibited significant antimicrobial action against Klebsiella pneumoniae, Fusarium oxysporum and Penicillium glabrum at a minimum inhibitory concentration (MIC) value of 3.12 μg mL-1, which is equivalent to the MIC of the standard drug. trans-Butene-linked bis(pyranopyrazole) 3f was also associated with a good radical scavenging activity similar to that of ascorbic acid (a standard antioxidant).

Novel PTP1B enzyme inhibitor, preparation method and applications thereof

The present invention provides a novel PTP1B enzyme inhibitor, a preparation method and applications thereof, and particularly discloses a class of bis 2-substituted ethylene sulfonate compounds and a preparation method thereof, and uses of the bis 2-substituted ethylene sulfonate compounds as the PTP1B enzyme activity inhibitor. According to the present invention, the prepared novel compound has good PTP1B enzyme activity inhibition effect, and has the application value in preparation of drugs for treatment and prevention of diabetes and obesity.

Y-shaped bis-arylethenesulfonic acid esters: Potential potent and membrane permeable protein tyrosine phosphatase 1B inhibitors

Known PTP1B inhibitors with bis-anionic moieties exhibit potent inhibitory activity, good selectivity, however, they are incapable of penetrating cellular membranes. Based upon our finding of a new pharmacophoric group in inhibition of PTP1B and the struc

Microwave assisted multi-component synthesis of novel bis(1,4-dihydropyridines) based arenes or heteroarenes

A synthesis of novel bis-1,4-DHPs was reported. Two possible synthetic approaches for these compounds were investigated. In the first approach the monopodal 1,4-DHPs were used as building blocks for the construction of the target molecules via a simple al

Synthesis, characterization, and antimicrobial studies of new rigid linker-based bispyrazolines

The bispyrazolines 4a-4e were synthesized from the cyclization reaction of bischalcones 3a-3e with phenyl hydrazine by refluxing under alcoholic medium in the presence of glacial acetic acid. The bischalcones were obtained from the Claisen-Schmidt reactio

Synthesis and antimicrobial studies of new N,N'-[5,5'-{2,2'-(bis-alkoxy) bis(2,1-phenylene)]bis(4-acetyl-4,5-dihydro-1,3,4-thiadiazole-5, 2-diyl)]diacetamide

The bisthiadiazolines 4a(a'-f ') and 4b(a'-f ') built around the various rigid chains have been synthesized in good yields by refluxing bisthiosemicarbazones 3a(a'-f ') and 3b(a'-f ') in acetic anhydride medium. The reaction of bisaldehydes 2a(a'-f ') and