64635-91-2Relevant academic research and scientific papers
Alkyl radical generation in water under ambient conditions - A new look at the Guareschi reaction of 1897
Nguyen, Bao,Chernous, Katya,Endlar, Daniel,Odell, Barbara,Piacenti, Michela,Brown, John M.,Dorofeev, Alexander S.,Burasov, Alexander V.
, p. 7655 - 7658 (2008/09/18)
(Chemical Equation Presented) Chemical and biochemical significance of a long-forgotten 19th century observation: The hydrocarbon production from quaternary glutarimides on neutralization in water is the consequence of formation of alkyl radicals, which means that it is possible to generate alkyl radicals under very mild conditions. Oxygen trapping competes with hydrogen abstraction (see scheme).
Geminate-Substituted Cyclopentadienes. 1. Synthesis of 5,5-Dialkylcyclopentadienes via 4,4-Dialkylcyclopent-2-en-1-ones.
Holder, Richard W.,Daub, John P.,Baker, Wesley E.,Gilbert, Raymond H,Graf, Norman A.
, p. 1445 - 1451 (2007/10/02)
A synthetic route for the preparation of 5,5,-dialkylcyclopentadienes (1) via 4,4-dialkylcyclopent-2-en-1-ones (3) is described.Beginnig with ketones (in which the two carbonyl substituents will become the two alkyl groups in the title compounds), the route traverses the Guareschi imides 5, 3,3-dialkylglutaric acids 4 and their ethyl esters 7, masked acyloins 8, cyclopentenones 3, alkohols 9, and bromides 10 to reach the dienes 1.Physical properties of five such derivates 1 and 3 (dimethyl, methylethyl,diethyl, methyl-n-propyl, and methylisopropyl) are presented.
2-[4-[(4,4-DIALKYL-2,6-PIPERIDINEDION-1-yl)BUTYL]-1-PIPERAZINYL]PYRIDINES
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, (2008/06/13)
1-4-(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl!piperazines with 2-2-(3-cyano)pyridyl substituents in the 4-position have been synthesized and demonstrate useful psychotropic properties.
