646483-08-1

Basic information

• Product Name: 4-hydroxy-5-Methyl-5-octylthiophen-2(5H)-one
• Synonyms: 4-hydroxy-5-Methyl-5-octylthiophen-2(5H)-one;PIRZFZMRZHTILE-UHFFFAOYSA-N
• CAS NO: 646483-08-1
• Molecular Formula: C₁₃H₂₂O₂S
• Molecular Weight: 242.37758
• Mol File: 646483-08-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 353.5±42.0 °C(Predicted)
• Appearance: /
• Density: 1.063±0.06 g/cm3(Predicted)
• PKA: 4.50±1.00(Predicted)
• CAS DataBase Reference: 4-hydroxy-5-Methyl-5-octylthiophen-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxy-5-Methyl-5-octylthiophen-2(5H)-one(646483-08-1)
• EPA Substance Registry System: 4-hydroxy-5-Methyl-5-octylthiophen-2(5H)-one(646483-08-1)

Safety Data

• Hazardous Substances Data: 646483-08-1(Hazardous Substances Data)

Upstream product

• 71091-89-9 n-octyl triflate 
• 1198410-66-0 (S,S)-2-tert-butyl-4-methyl-4-octyl-[1,3]oxathiolan-5-one 
• 1198410-71-7 C₁₃H₂₆O₂S 
• 111-87-5 octanol 
• 646483-04-7 2-mercapto-2-methyl-decanoic acid ethyl ester 
• 646483-06-9 (+/-)-2-acetylsulfanyl-2-methyldecanoic acid ethyl ester 
• 1024810-14-7 2,2,4-trimethyl-4-octyl-[1,3]oxathiolan-5-one 

Downstream Products

• 646482-93-1 (+/-)-(5-methyl-5-octyl-2-oxo-5H-thiophen-4-yloxy)-acetic acid-N'-(4-chloro-phenyl)-hydrazide 
• 1198410-27-3 2-(2-methyl-2-octyl-5-oxo-2,5-dihydro-thiophen-3-yloxy)-N-phenylacetamide 
• 1198410-25-1 N-(4-chlorophenyl)-(5-methyl-5-octyl-2-oxo-thiophen-4-yloxy)-acetamide 

Relevant articles and documents

Application of a flexible synthesis of (5R)-thiolactomycin to develop new inhibitors of type I fatty acid synthase

Fatty acid synthase (FAS) catalyzes the synthesis of palmitate from the sequential condensation of an acetyl primer with two carbon units added from malonyl-CoA. Inhibition of the β-ketoacyl synthase domain of mammalian FAS leads to selective cytotoxicity

NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME

Compounds having the following general formula, pharmaceutical compositions comprising the compounds, and methods of treating cancer, obesity, and microbial infections using such compositions: wherein: R1 = H, C1-C20 alkyl, cycloalkyl, alkenyl, aryl, aryl