64674-12-0Relevant academic research and scientific papers
A method for determining the enantiomeric purity of profens
Coulbeck, Elliot,Eames, Jason
body text, p. 635 - 640 (2009/08/15)
A simple method for determining the enantiomeric purity of profens (based on the carbon skeleton of 2-phenylpropionic acid) is discussed. The enantiomeric purity of a given profen can be determined by stereospecific DCC self-coupling to give a statistical diastereoisomeric mixture of racemic and meso- anhydrides. The relative ratio of diastereoisomers formed can be related to the enantiomeric excess of the original carboxylic acid.
