64682-89-9

Basic information

• Product Name: benzyl N-(2-hydroxyphenyl)carbamate
• Synonyms: benzyl N-(2-hydroxyphenyl)carbamate
• CAS NO: 64682-89-9
• Molecular Weight: 243.262
• Mol File: 64682-89-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: benzyl N-(2-hydroxyphenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl N-(2-hydroxyphenyl)carbamate(64682-89-9)
• EPA Substance Registry System: benzyl N-(2-hydroxyphenyl)carbamate(64682-89-9)

Safety Data

• Hazardous Substances Data: 64682-89-9(Hazardous Substances Data)

Upstream product

• 5366-26-7 <2-Nitro-phenyl>--ether 
• 88-75-5 2-hydroxynitrobenzene 
• 501-53-1 benzyl chloroformate 
• 95-55-6 2-amino-phenol 

Downstream Products

• 110877-44-6 [2-(2-piperidino-ethoxy)-phenyl]-carbamic acid benzyl ester 
• 1407484-74-5 benzyl 2H-benzo[b][1,4]oxazine-4(3H)-carboxylate 
• 376592-93-7 3′-amino-2′-hydroxy biphenyl-3-carboxylic acid 

Relevant articles and documents

PIFA-Promoted, Solvent-Controlled Selective Functionalization of C(sp2)-H or C(sp3)-H: Nitration via C-N Bond Cleavage of CH3NO2, Cyanation, or Oxygenation in Water

A novel nitration (via C(sp3)-N breaking/C(sp2)-N formation with CH3NO2) mediated by [bis(trifluoroacetoxy)iodo]benzene (PIFA) is described. The NO2 transfer from CH3NO2 to the aromatic group of the substrate is possible with careful selection of the solvent, NaX, and oxidant. In addition, the solvent-controlled C(sp2)-H functionalization can shift to an α-C(sp3)-H functionalization (cyanation or oxygenation) of the α-C(sp3)-H of cyclic amines.

DIHYDRO 1,4-BENZOXAZINES AND METHOD OF SYNTHESIZING THE SAME USING SULFONIUM SALTS

Exemplary embodiments of the present invention relate to benzoxazines having various N-protecting groups. An R1 functional group is at least one selected from the group consisting of H and a halogen, an R2 functional group is at least one selected from the group consisting of H, an amide, or a carbamate, and a Z functional group is at least one selected from the group consisting of a phenyl, substituted phenyl group, methyl, and t-butyl group. The exemplary embodiments provide compounds with benzoxazines having various cleavable protecting groups such as amides and carbamates.

Amberlyst-15 catalyzed Cbz protection of amines under solvent-free conditions

Amberlyst-15 can effectively catalyze Cbz protection of aliphatic and aromatic amines within 10-15 min under solvent-free conditions. The catalyst can be used repeatedly without loss of activity, and the reaction requires no workup and gives excellent yields. Taylor & Francis Group, LLC.