64686-07-3Relevant academic research and scientific papers
Synthesis of methyl 2,3-diaryl-3-methoxypropanoates by oxidative rearrangement of chalcones using hypervalent iodine reagents in trimethyl orthoformate
Singh,Garg,Kapoor
, p. 1025 - 1026 (2007/10/02)
A diastereoselective synthesis of methyl 2,3-diaryl-3-methoxypropanoates 8a-f by oxidative rearrangement of chalcones 1a-f using (diacetoxyiodo)benzene and hydroxy(tosyloxy)iodobenzene in trimethyl orthoformate is described.
Thallium in Organic Synthesis. 57. Reaction of Chalcones and Chalcone Ketals with Thallium(III) Trinitrate
Taylor, Edward C.,Conley, Richard A.,Johnson, David K.,McKillop, Alexander,Ford, Michael E.
, p. 3433 - 3436 (2007/10/02)
Treatment of chalcones (ArCH=CHCOAr') with thallium(III) trinitrate (TTN) in acidic methanol or in trimethyl orthoformate (TMOF) gives 3,3-dimethoxy-1,2-diarylpropan-1-ones (oxythallation, Ar rearrangement) and/or methyl 2,3-diaryl-3-methoxypropanoates (in situ ketal formation, oxythallation, Ar' rearrangement).The effect of substituents on Ar and Ar' on the ratio of the above rearrangement products has been examined.
