6469-54-1

Usage

Physical form

White to yellow crystalline powder

+ Xanthene core

A polycyclic aromatic structure with a central ring of six carbon atoms and two additional carbon atoms on each end.

+ Hexahydro substitution

The presence of six hydrogen atoms on the xanthene core, which gives the compound a more hydrophilic character.

+ Tetramethyl substitution

Four methyl groups (CH3) attached to the xanthene core, which can influence the compound's solubility and stability.

+ 2-Hydroxyphenyl group

A phenolic ring with a hydroxyl group (OH) attached to the ninth carbon of the xanthene core, which can participate in hydrogen bonding and other interactions.

+ Organic chemistry

The compound's unique structure may be useful in the synthesis of other complex molecules.

+ Pharmaceuticals

The compound may have potential as a drug candidate or as a building block in drug development.

Safety considerations

The potentially hazardous nature of the compound requires caution when handling and using it. Further research is needed to fully understand its potential uses and effects.

Upstream product

• 1689-72-1 2-([2]Naphthylimino-methyl)-phenol 
• 126-81-8 dimedone 
• 119150-29-7 5,5,5',5'-tetramethyl-2,2'-salicylidene-bis-cyclohexane-1,3-dione 
• 64-19-7 acetic acid 
• 90-02-8 salicylaldehyde 

Downstream Products

• 15781-65-4 9-(2'-acetoxyphenyl)-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8-octahydro-9H-xanthen-1,8-dione 
• 1365618-41-2 3,3,6,6-tetramethyl-9-[2-(prop-2-yn-1-yloxy)phenyl]-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione 
• 1365618-42-3 9-(2-(3-(4-hydroxyphenyl)prop-2-ynyloxy)phenyl)-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione 

Relevant academic research and scientific papers

Introduction of a trinuclear manganese(iii) catalyst on the surface of magnetic cellulose as an eco-benign, efficient and reusable novel heterogeneous catalyst for the multi-component synthesis of new derivatives of xanthene

In this work, the new trinuclear manganese catalyst defined as Fe3O4@NFC@NNSM-Mn(iii) was successfully manufactured and fully characterized by different techniques, including FT-IR, XRD, TEM, SEM, EDX, VSM, and ICP analysis. There have been reports of the use of magnetic catalysts for the synthesis of xanthine derivatives. The critical potential interest in the present method include short reaction time, high yields, recyclability of the catalyst, easy workup, and the ability to sustain a variety of functional groups, which give economical as well as ecological rewards. Also, the synthesized catalyst was used as a recyclable trinuclear catalyst in alcohol oxidation reactions at 40 °C. The magnetic catalyst activity of Fe3O4@NFC@NNSM-Mn(iii) could be attributed to the synergistic effects of the catalyst Fe3O4@NFC@NNS-Mn(iii) with melamine. Employing a sustainable and safe low temperature, using an eco-friendly solvent, no need to use any additive, and long-term stability and magnetic recyclability of the catalyst for at least six successive runs are the advantages of the current protocol towards green chemistry. This protocol is a benign, environmentally friendly method for heterocycle synthesis. This journal is

Sustainable synthesis of 1,8-dioxooctahydroxanthenes in deep eutectic solvents (DESs)

Deep eutectic solvents are obtained by the fusion of two or more compounds: hydrogen bond donors (HBDs) and hydrogen bond acceptors (HBAs). They are formed by mixing the constituents with moderate heating (via hydrogen bond interactions). In this manuscript, the dual activities (as catalysts and reaction media) of six deep eutectic solvents were compared for the synthesis of 1,8-dioxooctahydroxanthenes at room temperature. Here DES 2, a combination of ZrOCl2·8H2O with ethylene glycol at a 1 : 2 ratio, was found to be the supreme catalyst among the six DESs and was reused for five batches. The photophysical properties of the xanthene derivatives were examined by UV-vis and fluorescence spectroscopy in THF. The synthesised molecules showed absorption maxima around 285-295 nm and emission maxima around 403-404 nm. The ground state dipole moments of all the molecules were calculated by the Debye-Guggenheim method using toluene as the non-polar solvent. All the synthesised molecules showed significant dipole moment values and are in good agreement with theoretical values.

Incorporation of Keggin-based H3PW7Mo5O40into bentonite: synthesis, characterization and catalytic applications

The Keggin-based molybdo-substituted tungstophosphoric acid, H3[PW7Mo5O40]·12H2O, were synthesized and incorporated with a bentonite clay by using a wetness impregnation method. The catalysts were cha

Synthesis of Fe3O4-PVP nanocomposite functionalized with sulfonic group as an effective catalyst for one-pot synthesis of xanthene derivatives

An effective and environmentally friendly Fe3O4-PVP nanocomposite functionalized with sulfonic group, Fe3O4-PVP-SO3H, was synthesized and characterized as the heterogeneous nanocatalyst for one-pot sy

Magnetic Fe–Cr–Ni oxide alloy nano-belts prepared from the chemical decomposition of a stainless steel screw (a top-down approach): an efficient and cheap catalyst for multicomponent reactions

Abstract: A new, cheap, and accessible method has been used for the preparation of nano-belts from the chemical decomposition (top-down approach) of a cheap stainless steel screw and found as an efficient magnetically recyclable nanocatalyst for the prepa

Immobilized copper-layered nickel ferrite on acid-activated montmorillonite, [(NiFe2O4?Cu)(H+-Mont)], as a superior magnetic nanocatalyst for the green synthesis of xanthene derivatives

In this study, the immobilization of copper-layered nickel ferrite on the surface and in the cavities of acid-activated montmorillonite (H+-Mont) was investigated. In this context, magnetic nanoparticles (MNPs) of NiFe2O4

Calcined oyster shell nanoparticles (COS NPs): a new, efficient and reusable catalyst for one-pot rapid preparation of 1,8-dioxo-octahydroxanthenes under solvent-free conditions

Calcined oyster shell nanoparticles (COS NPs) as a novel heterogeneous nanocatalyst were prepared and fully characterized by X-ray fluorescence analysis, Fourier transform infrared spectroscopy, X-ray powder diffraction, scanning electron microscopy equip

Fly ash supported NiO as an efficient catalyst for the synthesis of xanthene and its molecular docking study against plasmodium glutathione reductase

A novel fly ash supported NiO (FA–NiO) nanocomposite solid heterogeneous catalyst has been prepared by impregnation of Ni(NO3)2 · 6H2O on thermally activated fly ash (FA) support. FT-IR spectroscopy, X-ray diffraction anal

Solvent-free Synthesis of 1,8-Dioxo-octahydroxanthenes and Tetra-hydrobenzo[a]xanthene-11-ones over Poly(N,N′-dibromo-N-ethylnaphtyl-2,7-sulfonamide)

In this work, poly(N,N′-dibromo-N-ethylnaphtyl-2,7-sulfonamide) (PDNES) as a highly efficient catalyst was applied for the synthesis of 1,8-dioxo-octahydroxanthenes and tetra-hydrobenzo[a]xanthene-11-ones under neutral and solvent-free conditions.