64692-81-5

Basic information

• Product Name: N'-(4,4-dimethylcyclohexylidene)-4-methylbenzene-1-sulfonohydrazide
• Synonyms: N'-(4,4-dimethylcyclohexylidene)-4-methylbenzene-1-sulfonohydrazide
• CAS NO: 64692-81-5
• Molecular Weight: 294.418
• Mol File: 64692-81-5.mol

Chemical Properties

• CAS DataBase Reference: N'-(4,4-dimethylcyclohexylidene)-4-methylbenzene-1-sulfonohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-(4,4-dimethylcyclohexylidene)-4-methylbenzene-1-sulfonohydrazide(64692-81-5)
• EPA Substance Registry System: N'-(4,4-dimethylcyclohexylidene)-4-methylbenzene-1-sulfonohydrazide(64692-81-5)

Safety Data

• Hazardous Substances Data: 64692-81-5(Hazardous Substances Data)

Upstream product

• 4255-62-3 4,4-dimethylcyclohexane-1-one 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 14072-86-7 4,4-dimethylcyclohexene 
• 1393683-13-0 (2-(4,4-dimethylcyclohexylidene)ethyl)benzene 
• 859217-67-7 2-(4,4-dimethylcyclohex-1-ene-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 865869-28-9 (4,4-dimethylcyclohex-1-en-1-yl)boronic acid 
• 1142363-60-7 6-(2,2,6,6-tetramethyl-tetrahydro-pyran-4-yl)-pyridin-3-ylamine 
• 1142363-64-1 2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-amine 
• 536-57-2 p-toluene sulfinic acid 

Relevant articles and documents

Copper-catalyzed tri- or tetrafunctionalization of alkenylboronic acids to prepare tetrahydrocarbazol-1-ones and indolo[2,3-a]carbazoles

We describe a cascade strategy for tri- or tetrafunctionalization of alkenylboronic acids to prepare diverse tetrahydrocarbazol-1-ones and indolo[2,3-a]carbazoles in good yields withN-hydroxybenzotriazin-4-one (HOOBT) and arylhydrazines as oxygen and nitrogen sources, respectively. Mechanistic studies reveal that the domino reaction undergoes the copper-catalyzed Chan-Lam reaction, [2,3]-rearrangement, nucleophilic substitution, oxidation and sequential [3,3]-rearrangement over five steps in a one-pot reaction. The reaction shows a broad substrate scope and tolerates a wide range of functional groups. More importantly, the reaction is easily performed at gram scales and the product is purified by simple extraction, washing, and recrystallization without flash column chromatography. The present protocol features easily available starting materials, high site-marked functionalization, five-step cascade in one pot, multiple C-C/C-O/C-N bond formation, and diversity of indole motifs.