859217-67-7

Basic information

• Product Name: 4,4-(DIMETHYLCYCLOHEXENE-1-YL)BORONIC ACID, PINACOL ESTER
• Synonyms: 4,4-DiMethylcyclohexenylboronic acid pinacol ester;4,4-Dimethylcyclohexene-1-boronic Acid Pinacol Ester;4,4-(Dimethylcyclohexen-1-yl)boronic acid pinacol ester 2-(4,4-Dimethyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-(4,4-Dimethylcyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-(4,4-Dimethyl-1-cyclohexen-1-yl);4,4-(DIMETHYLCYCLOHEXENE-1-YL)BORONIC ACID, PICOL ESTER;4,4-(DIMETHYLCYCLOHEXENE-1-YL)BORONIC ACID, PINACOL ESTER;4,4-(Dimethylcyclohexen-1-yl)boronic acid pinacol ester
• CAS NO: 859217-67-7
• Molecular Formula: C₁₄H₂₅BO₂
• Molecular Weight: 236.161
• Product Categories: Alkyl;Organoborons
• Mol File: 859217-67-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 255℃
• Flash Point: 108℃
• Appearance: /
• Density: 0.94
• Vapor Pressure: 0.027mmHg at 25°C
• Refractive Index: 1.466
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4,4-(DIMETHYLCYCLOHEXENE-1-YL)BORONIC ACID, PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-(DIMETHYLCYCLOHEXENE-1-YL)BORONIC ACID, PINACOL ESTER(859217-67-7)
• EPA Substance Registry System: 4,4-(DIMETHYLCYCLOHEXENE-1-YL)BORONIC ACID, PINACOL ESTER(859217-67-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 859217-67-7(Hazardous Substances Data)

Usage

Uses

4,4-Dimethylcyclohexen-1-ylboronic acid, pinacol ester

InChI:InChI=1/C14H25BO2/c1-12(2)9-7-11(8-10-12)15-16-13(3,4)14(5,6)17-15/h7H,8-10H2,1-6H3

Upstream product

• 4255-62-3 4,4-dimethylcyclohexane-1-one 
• 61676-62-8 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 64692-81-5 N'-(4,4-dimethylcyclohexylidene)-4-methylbenzene-1-sulfonohydrazide 
• 98056-47-4 trifluoromethanesulfonic acid 4,4-dimethyl-cyclohex-1-enyl ester 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 915006-34-7 4-amino-N-tert-butyl-3-(4,4-dimethyl-cyclohex-1-enyl)-benzenesulfonamide 
• 915006-35-8 2-[4-amino-3-(4,4-dimethyl-cyclohex-1-enyl)-phenyl]-ethanesulfonic acid tert-butyl amide 
• 865869-28-9 (4,4-dimethylcyclohex-1-en-1-yl)boronic acid 
• 1354491-07-8 (S)-ethyl 2-tert-butoxy-2-(1-(4,4-dimethylcyclohex-1-enyl)-3-methylnaphthalen-2-yl)acetate 
• 915006-36-9 4-cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylic acid [4-(2-(tert-butylsulfamoyl)-ethyl)-2-(4,4-dimethyl-cyclohex-1-enyl)-phenyl]-amide 
• 915006-33-6 4-cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylic acid [4-tert-butylsulfamoyl-2-(4,4-dimethyl-cyclohex-1-enyl)-phenyl]-amide 

Relevant articles and documents

N-(PYRIDIN-2-YLSULFONYL)CYCLOPROPANECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF A CFTR MEDIATED DISEASE

The invention relates to heterocyclic compounds of the formula (I), in which all of the variables are as defined in the specification; capable of modulating the activity of CFTR. The invention further provides a method for manufacturing compounds of the invention, and its therapeutic uses. The invention further provides methods to their preparation, to their medical use, in particular to their use in the treatment and management of diseases or disorders including Cystic fibrosis and related disorders.

Interrupted fischer-indole intermediates via oxyarylation of alkenyl boronic acids

The oxyarylation of alkenyl boronic acids with N-arylbenzhydroxamic acids has been achieved under both copper-mediated and copper-catalyzed conditions to provide access to interrupted Fischer-indole intermediates. This transformation is believed to proceed through a copper-promoted C-O bond forming event followed by a [3,3] rearrangement. The scope of the method is described and mechanistic experiments are discussed.

4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS

Novel antiviral compounds of Formula (I) : wherein: A represents hydroxy; R1 represents aryl, heteroaryl bonded through a ring carbon atom, or heterocyclyl bonded through a ring carbon atom, C1-6alkyl or -C5-9cycloalkyl, each of which may be optionally su