646996-53-4Relevant academic research and scientific papers
Synthesis of functionalized 1-azaspirocyclic cyclopentanones using bronsted acid or N-bromosuccinimide promoted ring expansions
Dake, Gregory R.,Fenster, Michael D. B.,Hurley, Paul B.,Patrick, Brian O.
, p. 5668 - 5675 (2004)
Azaspirocyclic ring systems are present in a variety of alkaloids. Functionalized 1-azaspirocyclopentanones (6, 7, 11, 12) can be efficiently constructed through semipinacol ring expansion reactions of 2-(1- hydroxycyclobutyl)-p-toluenesulfonylenamides (4
