647014-06-0

Usage

Molecular weight

363.8 g/mol

Structure

A piperidine ring with a carboxyl group, a phenoxy group, a chlorine atom, and a trifluoromethyl group.

Functional groups

Tert-butyl ester, phenoxy, and halogen (chlorine) substituents.

Applications

Pharmaceutical and agricultural industries as a building block in the synthesis of various pharmaceuticals and agrochemicals.

Research and development

Potential use in the discovery of new drugs and crop protection products.

Upstream product

• 35852-58-5 2-chloro-4-trifluoromethylphenol 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Downstream Products

• 647014-08-2 4-[2-chloro-4-(trifluoromethyl)phenoxy]piperidine trifluoroacetate 

Relevant academic research and scientific papers

NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS

The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds, methods of using the compounds and methods of determining the monoacylglycerol lipase (MAGL) inhibitory activity of the compounds.

NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS

The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.

SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS

A compound of formula (1), wherein B is an ortho substituted monocyclic aryl or heteroaryl group or a bicyclic aryl or heteroaryl group; useful in the inhibition of one or more metalloproteinases, and in particular TACE.