647036-89-3Relevant academic research and scientific papers
N-SULFONYLPIPERIDINES AS METALLOPROTEINASE INHIBITORS (TACE)
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Page/Page column 52, (2010/02/06)
Compounds of formula (1), wherein Z is -CONR15OH or -N(OH)CHO and X is -(CR9R10)t-Q-(CR11R12)u- (where t and u are independently 0 or 1 with the proviso that t and u cannot both be 0);are inhibitors o
1-SULPHONYL PIPERIDINE DERIVATIVES
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Page 43, (2010/02/06)
Piperidine derivatives of formula (1) that are useful in the inhibition of metalloproteinases, in particular TNF-α Converting Enzyme (TACE) and thus in the treatment of autoimmune disease, allergic/atopic diseases, transplant rejection, graft versus host disease, cardiovascular disease, reperfusion injury and malignancy.
