64748-64-7Relevant articles and documents
STUDIES IN THE FIELD OF NITROGEN HETEROCYCLIC COMPOUNDS. PART XIII. THERMAL RING OPENING - RING CLOSURE REARRANGEMENT OF ARYLO- AND HETEROARYLO-SUBSTITUTED PYRAZOLOPYRIMIDINES INTO PYRAZOLOPYRIDINES
Balicki, Roman
, p. 1219 - 1230 (2007/10/02)
A reaction of β-ketoesters 1a, 1j with 3-amino-1-methylpyrazole (2a) in ethanol leads to formation of enamines 3a, 3j, whereas in acetic acid or without solvent at 110 deg C, the corresponding amides 6a, 6j were produced.Compounds 3a, 3j undergo cyclizati