64765-90-8 Usage
Uses
Used in Pharmaceutical Industry:
(Z)-2-FORMYLAMINO-3-PHENYL-ACRYLIC ACID METHYL ESTER is used as a building block for the synthesis of various biologically active compounds, contributing to the development of new pharmaceuticals. Its formylamino and phenyl groups, along with the acrylate group, make it a valuable component in the creation of small molecule inhibitors for medicinal purposes.
Used in Agrochemical Industry:
In the agrochemical industry, (Z)-2-FORMYLAMINO-3-PHENYL-ACRYLIC ACID METHYL ESTER is utilized in the production of agrochemicals, such as pesticides and herbicides. Its unique structure allows for the development of compounds that can effectively target and control pests and weeds in agricultural settings.
Used in Organic Synthesis:
(Z)-2-FORMYLAMINO-3-PHENYL-ACRYLIC ACID METHYL ESTER is also used as a reagent in organic synthesis, where its functional groups can be manipulated to create a wide range of chemical products. The methyl ester group, in particular, is useful for the synthesis of small molecule inhibitors, further expanding its applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 64765-90-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,7,6 and 5 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 64765-90:
(7*6)+(6*4)+(5*7)+(4*6)+(3*5)+(2*9)+(1*0)=158
158 % 10 = 8
So 64765-90-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H11NO3/c1-15-11(14)10(12-8-13)7-9-5-3-2-4-6-9/h2-8H,1H3,(H,12,13)/b10-7-
64765-90-8Relevant academic research and scientific papers
Metal-Free Radical Cyclization of Vinyl Isocyanides with Alkanes: Synthesis of 1-Alkylisoquinolines
Xue, Dengqi,Xue, Yijie,Yu, Haihua,Shao, Liming
supporting information, p. 874 - 884 (2019/02/10)
A metal-free radical cyclization reaction of vinyl isocyanides with alkanes is developed, allowing convenient access to a diverse range of potentially valuable 1-alkylisoquinolines. The methodology is simple and efficient, demonstrating excellent functional group tolerance and broad substrate scope. A mechanism involving a radical process is supported by kinetic isotope effect and radical inhibition studies.
Screening multicomponent reactions for X-linked inhibitor of apoptosis-baculoviral inhibitor of apoptosis protein repeats domain binder
Monfardini, Ilaria,Huang, Jui-Wen,Beck, Barbara,Cellitti, Jason F.,Pellecchia, Maurizio,Domling, Alexander
scheme or table, p. 890 - 900 (2011/04/22)
We report a second example of a general reaction screening approach to discover low molecular weight inhibitors of protein protein interactions. On the basis of the known pharmacophore model of SMAC mimetics, we predicted several inhibitors based on four
2,4,5-Trisubstituted thiazole building blocks by a novel multi-component reaction
Umkehrer, Michael,Kolb, Jürgen,Burdack, Christoph,Hiller, Wolfgang
, p. 79 - 82 (2007/10/03)
A novel multi-component reaction (MCR) of oxo-components, primary amines, thiocarboxylic acids and 3-bromo-2-isocyanoacrylates yielding 2,4,5-trisubstituted thiazole building blocks is described.
