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Ethanol, 2-(2,4,6-trinitrophenoxy)-, also known as trinitrophenyl ethanol or TNP-EtOH, is a chemical compound with the molecular formula C8H7N3O7. It is a derivative of ethanol, where one of the hydroxyl groups is replaced by a 2,4,6-trinitrophenoxy group. Ethanol, 2-(2,4,6-trinitrophenoxy)- is primarily used as a hapten in immunoassays, particularly in the detection of antibodies against the 2,4,6-trinitrophenol (TNP) group. TNP-EtOH is a small molecule that can be conjugated to larger molecules, such as proteins, to create antigens that can be recognized by the immune system. This property makes it a valuable tool in research and diagnostics, particularly in the development of tests for the presence of specific antibodies.

6478-31-5

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6478-31-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6478-31-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,7 and 8 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6478-31:
(6*6)+(5*4)+(4*7)+(3*8)+(2*3)+(1*1)=115
115 % 10 = 5
So 6478-31-5 is a valid CAS Registry Number.

6478-31-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2,4,6-trinitrophenoxy)ethanol

1.2 Other means of identification

Product number -
Other names 2-picryloxy-ethanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6478-31-5 SDS

6478-31-5Relevant academic research and scientific papers

Transient Nitronic Acid Formation in the Acid-Catalyzed Decomposition of Nitrobenzofuroxan and Nitrobenzofurazan ?-Adducts in Methanolic Solution. A Kinetic Study

Terrier, Francois,Ah-Kow, Guy,Chatrousse, Alain-Pierre

, p. 4583 - 4589 (1985)

Kinetic data for the acid-ctalyzed and uncatalyzed decomposition of the dioxolane spiro complexes of 7-(2-hydroxyethoxy)-4-nitrobenzofurazan and -benzofuroxan and of the 7,7-dimethoxy complexes of 7-methoxy-4-nitrobenzofurazan and -benzofuroxan have been obtained over a large pH range in methanol.The ring opening of the spiro complexes but not the methoxide ion departure from the dimethoxy adducts is found to be appreciably catalyzed by carboxylic acids.The corresponding Broensted α coefficients are equal to about 0.5, indicating concerted acid catalysis.At low pH, i.e., pH a values associated with the ionization of the resulting nitronic acids are all very similar and of the order of 4.2 - 4.5, as compared with estimated pKa values of about 1 - 2 for analogous nitronic acids of picryl ?-complexes.Kinetic data for the formation of the adducts are also reported.The marked differences observed in the rates of formation and decomposition of the similarly stable benzofurazan and benzofuroxan spiro adducts are interpreted in terms of electrostatic effects connected with the presence of the N-oxide group in the transition states for the benzofuroxan reactions.

REACTIONS OF AROMATIC NITRO COMPOUNDS. LXIV. ANIONIC ? COMPLEXES OF THE ALKYL ETHERS OF 2,4,6-TRINITROPHENOL WITH THE ALCOHOLATES OF DIHYDRIC AND TRIHYDRIC ALCOHOLS

Mel'nikov, A. I.,Gitis, S. S.,Kaminskii, A. Ya.

, p. 268 - 274 (2007/10/02)

Sodium 1-methoxy-1-(β-hydroxypropoxy)-2,4,6-trinitro-2,5-cyclohexadienide was obtained from 2,4,6-trinitroanisole and sodium 2-hydroxypropoxide.It was then converted into corresponding spirocyclic anionic ? complex.In the reaction of 2,4,6-trinitrophenetole with sodium 2-hydroxyethoxide, 3-hydroxypropoxide, and 4-hydroxybutoxide the 1-ethoxy-1-hydroxyalkoxyl ? complexes are formed at the first stage and are then converted into spirocyclic and 1,1-dihydroxyalkoxyl ? complexes.Spirocyclization only takes place in the presence of the β-hydroxy group.The transformations are realized with the participation of the glycol ethers of 2,4,6-trinitrophenol, which are formed in the reaction as transetherification products.

REACTIONS OF AROMATIC NITRO COMPOUNDS. LX. MECHANISM OF TRANSFORMATIONS OF SODIUM 6,8,10-TRINITRO-1,4-DIOXASPIRODECA-6,9-DIENIDE IN AN ACIDIC MEDIUM

Shakhkel'dyan, I. V.,Glaz, A. I.,Gitis, S. S.

, p. 2176 - 2179 (2007/10/02)

The effect of 2,4,6-trinitrophenol on the decomposition rate of sodium 6,8,10-trinitro-1,4-dioxaspirodeca-6,9-dienide in aqueous and water-dimethyl sulfoxide media was investigated.It was shown that the 1-(β-hydroxyethoxy)-2,4,6-trinitrobenzene formed during the decomposition of sodium 6,8,10-trinitro-1,4-dioxaspirodeca-6,9-dienide isomerizes with the formation of a spirocyclic quinolnitronic acid.Proton transfer in the isomerization takes place by an intermolecular mechanism with the participation of water.

REACTIONS OF AROMATIC NITRO COMPOUNDS. LVII. REACTION OF GLYCOL ETHERS OF PICRIC ACID WITH NUCLEOPHILIC AGENTS

Mel'nikov, A. I.,Gitis, S. S.,Kaminskii, A. Ya.

, p. 1336 - 1343 (2007/10/02)

In the reaction of the glycol ethers of picric acid, containing 2-4 methylene units, with alkali-metal methoxides, tert-butoxides, and glycolates the intermolecular 1,1-?-complexes are formed in addition to the intamolecular spirocyclic anionic ? complexes.Thus, irrespective of the nature of the solvent and the nucleophilic agent, 1-(β-hydroxyethoxy)-2,4,6-trinitrobenzene undergoes intramolecular spirocyclization to a ? complex with a 1,3-dioxolane spirocycle.For 1-(δ-hydroxybutoxy)-2,4,6-trinitrobenzene only the formation of intermolecular 1-methoxy-1-hydroxyalkoxy- and 1,1-dihydroxyalkoxy-2,4,6-trinitrocyclohexa-2,5-dienides is observed, whereas 1-(γ-hydroxypropoxy)-2,4,6-trinitrobenzene can give ? complexes of both types, depending on the polarity of the solvent.

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