7388-28-5

Basic information

• Product Name: sodium 2-hydroxyethanolate
• CAS NO: 7388-28-5
• Molecular Formula: C₂H₄O₂*2Na
• Molecular Weight: 84.0497
• Mol File: 7388-28-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 197.5°C at 760 mmHg
• Flash Point: 108.2°C
• Vapor Pressure: 0.0959mmHg at 25°C
• CAS DataBase Reference: sodium 2-hydroxyethanolate(CAS DataBase Reference)
• NIST Chemistry Reference: sodium 2-hydroxyethanolate(7388-28-5)
• EPA Substance Registry System: sodium 2-hydroxyethanolate(7388-28-5)

Safety Data

• Hazardous Substances Data: 7388-28-5(Hazardous Substances Data)

Upstream product

• 107-21-1 ethylene glycol 
• 7440-23-5 sodium 
• 94-33-7 C₉H₁₀O₃ 

Downstream Products

• 856812-33-4 α-chloro-isobutyric acid ethylamide 
• 107-07-3 2-chloro-ethanol 
• 3669-46-3 1-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethanone 
• 94082-82-3 2-(5-chloro-2,4-dinitro-phenoxy)-ethanol 
• 874529-79-0 2-(3,4-dichloro-benzyloxy)-ethanol 
• 110-80-5 2-ethoxy-ethanol 
• 592-55-2 2-Bromoethyl ethyl ether 
• 83547-70-0 1-(2-hydroxyethoxy)-2,6-dinitro-4-chlorobenzene 
• 101530-99-8 2,2-Bis-(2-hydroxy-ethoxy)-1-phenyl-propan-1-one 
• 4403-13-8 2-(trimethylsilyloxy)ethanol 
• 108-41-8 1-chloro-3-methylbenzene 
• 56138-86-4 2-[2,2-Bis-(4-nitro-phenyl)-vinyloxy]-ethanol 
• 18370-23-5 Di--acetaldehyd-diaethylacetal 
• 174227-14-6 p-tert-butyl-N-[6-hydroxy-5-(2-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide 

Relevant articles and documents

Preparation method of ethylene sulfite

The preparation method comprises the following steps 1) adding ethylene glycol disodium salt into a solvent, adding thionyl chloride dropwise to a certain temperature under the protection of nitrogen, adding the sodium bicarbonate aqueous solution to neutrality after a period of time, and separating the organic phase. 2) The organic phase was dried over anhydrous sodium sulfate, the solvent was recovered at atmospheric pressure, and vinyl sulfite was obtained under reduced pressure. 1) The synthetic method disclosed by the invention has the following beneficial effects that the ethylene glycol disodium salt is taken as a raw material and reacted with thionyl chloride in a solvent to synthesize ethylene sulfite. , The production cost is reduced, and great economic benefits and social benefits are achieved.

Synthesis of Functionalized 1,4-Dioxanes with an Additional (Hetero)Aliphatic Ring

An approach to the preparation of 2-mono-, 2,2- and 2,3-disubstituted 1,4-dioxane derivatives is described. The reaction sequence commences from readily available epoxides, in most cases prepared via the Corey-Chaikovsky reaction of the corresponding aldehydes and ketones. The key step of the method is epoxide ring opening with ethylene glycol monosodium salt, followed by further cyclization of the diols obtained. The utility of the approach was demonstrated by multigram preparation of novel functionalized 1,4-dioxanes bearing additional cycloalkane, piperidine or pyrrolidine rings, mostly spirocyclic compounds, which are advanced building blocks for medicinal chemistry.

Solubility of potassium and sodium orthophosphates in ethylene glycol

Solubility of potassium and sodium orthophosphates in ethylene glycol was determined.