64781-75-5

Usage

Uses

Used in Pharmaceutical Applications:
[4-(ethoxycarbonyl)-3H-pyrazol-3-ylidene]diazenium is used as a building block for the development of new drug molecules due to its unique structure and reactivity. Its potential applications in the pharmaceutical industry are still being explored and researched by the scientific community.
Used in Materials Science:
[4-(ethoxycarbonyl)-3H-pyrazol-3-ylidene]diazenium is used as a valuable component in the creation of new functional materials. Its structure and properties make it a promising candidate for various applications in materials science.
Used in Organic Synthesis:
[4-(ethoxycarbonyl)-3H-pyrazol-3-ylidene]diazenium is used as a key intermediate in organic synthesis, allowing for the development of novel chemical compounds with potential applications in various industries.

Upstream product

• 1260243-04-6 ethyl 5-amino-1H-pyrazole-4-carboxylate 

Downstream Products

• 58456-63-6 3-(3,3-dimethyl-triaz-1-enyl)-1(2)H-pyrazole-4-carboxylic acid ethyl ester 
• 73997-09-8 3,4-Dihydro-4-oxo-3-phenyl-pyrazolo<5,1-d>-1,2,3,5-tetrazin-8-carbonsaeure-ethylester 

Relevant academic research and scientific papers

Synthesis of new azolo[5,1-d][1,2,3,5]tetrazin-4-ones–analogs of antitumor agent temozolomide

Reactivity of 5-diazoimidazoles and 5-diazopyrazoles in the reactions with alkyland aryl isocyanates was studied. A number of new imidazo-and pyrazolo[5,1-d][1,2,3,5]tetrazin-4 ones were synthesized, which are analogs of temozolomide. It was shown that diazoazoles do not react with isothiocyanates under similar conditions.

Synthesis and structure of new imidazo- and pyrazolo[5,1-d][1,2,3,5] thiatriazines based on the reaction of diazoazoles with acyl isothiocyanates controlled by Sa?O interaction

5-Diazoimidazoles and 5-diazopyrazoles have been shown to react with acyl isothiocyanates yielding the imidazo- and pyrazolo[5,1-d][1,2,3,5]thiatriazines stabilized by a nonbonded Sa?O interaction. In contrast to acyl isothiocyanates, alkyl-, aryl-, and arylsulfonyl isothiocyanates do not react with 5-diazoazoles. The nature and the strength of stabilizing intramolecular interaction between non-bonded S and O atoms have been studied by X-ray analysis for mono crystals and DFT calculations for selected azolo[5,1-d][1,2,3,5] thiatriazines. The interaction was described in terms of Weinhold covalence ratio factors, NBO, and AIM schemes. The reaction discovered was used to develop an efficient approach toward the new 8-substituted 4-ethoxycarbonylimino-4- benzoyl- and 4-(3,4,5,6-tetrafluorobenzoyl)iminoimidazo(pyrazolo)[5,1-d][1,2,3, 5]thiatriazines.