647826-50-4Relevant academic research and scientific papers
Side-chain transformations of 6- and 7-substituted 1,3-dimethyllumazines (=1,3-dimethylpteridine-2,4(1H,3H)-diones)
Torigoe, Kiyoshi,Kariya, Naohiro,Soranaka, Kazuyuki,Pfleiderer, Wolfgang
, p. 1190 - 1205 (2008/03/13)
A series of side chain reactions starting from the 6- and 7-styryl-substituted 1,3-dimethyllumazines 1 and 21 as well as from the 6- and 7-[2-(methoxycarbonyl)ethenyl]-substituted 1,3-dimethyllumazine 2 and 22 were performed first by addition of Br2
Synthesis and heterocyclizations of 3-alkynyl-6,8-dimethylpyrimido-[4,5-c] pyridazine-5,7(6H,8H)-diones and their lumazine analogues
Gulevskaya, Anna V.,Van Dang, Shee,Pozharskii, Alexander F.
, p. 413 - 419 (2007/10/03)
Synthesis of some condensed pyrrolo-, thieno-, furo-, pyrido- and pyranopteridines as well as isomeric pyrrolo- and thienopyrimido[4,5-c] pyridazines from alkynyl derivatives of 6,8-dimethylpyrimido[4,5-c]pyridazine-5, 7(6H,8H)-dione and 1,3-dimethyllumaz
Purines, pyrimidines, and related fused systems 20.* Heterocyclizations of 6-alkynyl-1,3-dimethyllumazines. Synthesis of pyrrole and thiophene analogs of some natural pteridines
Gulevskaya,Van Shee, Dang,Pozharskii
, p. 1403 - 1410 (2007/10/03)
Sonogashira cross-coupling of 6-chloro-1,3-dimethyllumazine with terminal alkynes gave 6-alkynyl derivatives in good yields. Oxidative amination of the latter with primary alkylamines was accompanied by the pyrrole-ring closure to form 1-R′-2-R-6,8-dimeth
