84689-47-4

Basic information

• Product Name: 6-chloro-1,3-dimethyl-2,4(1H,3H)-pteridinedione
• Synonyms: 6-chloro-1,3-dimethyl-2,4(1H,3H)-pteridinedione
• CAS NO: 84689-47-4
• Molecular Formula: C₈H₇ClN₄O₂
• Molecular Weight: 226.61978
• Mol File: 84689-47-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-chloro-1,3-dimethyl-2,4(1H,3H)-pteridinedione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-1,3-dimethyl-2,4(1H,3H)-pteridinedione(84689-47-4)
• EPA Substance Registry System: 6-chloro-1,3-dimethyl-2,4(1H,3H)-pteridinedione(84689-47-4)

Safety Data

• Hazardous Substances Data: 84689-47-4(Hazardous Substances Data)

Upstream product

• 42347-09-1 1,3-dimethyl-5-oxy-1H-pteridine-2,4-dione 
• 61846-18-2 1,3-Dimethyl-6-oxo-5,6-dihydrolumazin 
• 61846-18-2 1,3-dimethylpteridine-2,4,6(1H,3H,5H)-trione 

Downstream Products

• 647826-46-8 1,3-dimethyl-6-(phenylethynyl)pteridine-2,4(1H,3H)-dione 
• 103262-72-2 1,3,5-Trimethylpteridin-2,4,6(1H,3H,5H)-trion 
• 647826-50-4 6-[(1E)-1,2-dibromo-2-phenylethenyl]-1,3-dimethylpteridine-2,4(1H,3H)-dione 

Relevant articles and documents

Recent advances in selective syntheses of 6- and 7-substituted pteridines

Novel regioselective methods for construction of biologically important pteridines which contain carbon substituents on the 6- or 7-position using pteridine ring-forming cyclocondensations, nucleophilic substitution reactions, and radical reactions are reviewed.

PURINES, PYRIMIDINES AND CONDENSED SYSTEMS BASED ON THEM. 10. REACTIVITY OF 1,3-DIMETHYL-6-CHLOROLUMAZINE WITH RESPECT TO AMINES: COMPETITION OF AMINODECHLORINATION AND AMINODEHYDROGENATION REACTIONS

1,3-Dimethyl-6-chlorolumazine reacts with secondary alkylamines and hydrazine to form 1,3-dimethyl-6-amino(hydrazino) derivatives in good yields.At the same time, 6-chloro-7-amino-1,3-dimethyllumazines are formed by the action of primary amines and liquid ammonia, in addition to the nucleophilic substitution products of chlorine.

Pteridines, LXXII. - Synthesis and Properties of 6- and 7-Amino-1,3-dimethyllumazines

The synthesis of 6- and 7-amino-, -methylamino-, and -dimethylamino-1,3-dimethyllumazines (2-4 and 12-14) is described.The nucleophilic displacement reaction proceeds easily with the 7-halo-1,3-dimethyllumazines 10, 11 whereas the amidation of 6-hydroxy-1,3-dimethyllumazine (1) with phenyl diamidophosphates is recommended for the formation of 6-amino derivatives. 6-Amino-1,3-dimethyllumazine (2) is synthesized best from 6-chloro-1,3-dimethyllumazine (7) via the 6-hydrazino derivative 5 and subsequent reduction.From pKa value determinations and UV absorption spectra of the cationic and neutral forms can be seen that protonation takes place in both series at N-5.The physical properties of the newly synthesized compounds are discussed.