64785-82-6

Basic information

• Product Name: Hexanoic acid, 6-oxo-6-(phenylamino)-, methyl ester
• CAS NO: 64785-82-6
• Molecular Formula: C13H17NO3
• Molecular Weight: 235.283
• Mol File: 64785-82-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Hexanoic acid, 6-oxo-6-(phenylamino)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanoic acid, 6-oxo-6-(phenylamino)-, methyl ester(64785-82-6)
• EPA Substance Registry System: Hexanoic acid, 6-oxo-6-(phenylamino)-, methyl ester(64785-82-6)

Safety Data

• Hazardous Substances Data: 64785-82-6(Hazardous Substances Data)

Upstream product

• 626-86-8 adipinic acid monoethyl ester 
• 62-53-3 aniline 
• 627-91-8 adipic acid monomethyl ester 
• 35444-44-1 methyl adipoyl chloride 

Downstream Products

• 56384-27-1 Hexanedioic acid hydroxyamide phenylamide 
• 1017261-00-5 5-(1H-indol-2-yl)-N-phenylpentanamide 
• 606092-25-5 6-[(methoxymethylphosphinyl)oxy]-N-phenylhexaneamide 
• 852619-57-9 hexanedioic acid phenylamide (2-tritylsulfanyl-ethyl)-amide 
• 606092-23-3 5-hydroxy-N-phenylpentanamide 
• 34413-03-1 6-Anilino-6-oxohexanoic acid 

Relevant articles and documents

A hydroxamic acid derivatives, its pharmaceutical composition, preparation method and use thereof

The invention belongs to the pharmaceutical chemicals field, and relates to a hydroxamic acid derivative, its pharmaceutical composition, a preparation method and an application. The invention relates to a compound shown in a formula I or a formula II, or

Carboxamidation of carboxylic acids with 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline (BBDI) without bases

Formation of carboxamides of a variety of carboxylic acids with the coupling reagent BBDI is described. This procedure permits a one pot and simple operation without the need of any bases and no base was?required for even use of amine hydrochlorides. In addition, an approach to BBDI-catalyzed carboxamidation is examined.

Mercaptoamide-based non-hydroxamic acid type histone deacetylase inhibitors

Inhibitors of histone deacetylases (HDAC) are emerging as a promising class of anti-cancer agents. A mercaptoamide functionality was designed as a bidentate zinc chelator and incorporated into the hydroxamic acid based SAHA (1) scaffold in order to identify non-hydroxamate compounds as potential inhibitors of histone deacetylases. Two sets of mercaptoamides 2 and 3 with varying spacer length were synthesized and their HDAC inhibitory activity was evaluated. Low micromolar inhibition was observed for mercaptoamides 2e, 3b, and 3d.