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2-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDIN-4-OL is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

647862-98-4

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647862-98-4 Usage

Core Structure

The compound has a tetrahydropyrido[3,4-d]pyrimidin-4-ol core structure.

Substituent

The core structure is attached with a trifluoromethyl group.

Potential Applications

The compound has potential applications in the pharmaceutical industry.

Use as Building Block

It can be used as a building block in the synthesis of various biologically active molecules.

Value in Medicinal Chemistry Research

The compound holds promise in medicinal chemistry research due to its unique structure and potential pharmacological properties.

Enhanced Stability

The presence of a trifluoromethyl group can provide enhanced chemical and metabolic stability, making it a valuable tool for drug discovery and development.

Check Digit Verification of cas no

The CAS Registry Mumber 647862-98-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,7,8,6 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 647862-98:
(8*6)+(7*4)+(6*7)+(5*8)+(4*6)+(3*2)+(2*9)+(1*8)=214
214 % 10 = 4
So 647862-98-4 is a valid CAS Registry Number.

647862-98-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(trifluoromethyl)-5,6,7,8-tetrahydro-1H-pyrido[3,4-d]pyrimidin-4-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:647862-98-4 SDS

647862-98-4Relevant academic research and scientific papers

The Role of the acidity of N-heteroaryl sulfonamides as inhibitors of Bcl-2 family protein-protein interactions

Touré, B. Barry,Miller-Moslin, Karen,Yusuff, Naeem,Perez, Lawrence,Doré, Michael,Joud, Carol,Michael, Walter,Dipietro, Lucian,Van Der Plas, Simon,McEwan, Michael,Lenoir, Francois,Hoe, Madelene,Karki, Rajesh,Springer, Clayton,Sullivan, John,Levine, Kymberly,Fiorilla, Catherine,Xie, Xiaoling,Kulathila, Raviraj,Herlihy, Kara,Porter, Dale,Visser, Michael

supporting information, p. 186 - 190 (2013/04/10)

Overexpression of the antiapoptotic members of the Bcl-2 family of proteins is commonly associated with cancer cell survival and resistance to chemotherapeutics. Here, we describe the structure-based optimization of a series of N-heteroaryl sulfonamides t

SULFONAMIDES AS INHIBITORS OF BCL-2 FAMILY PROTEINS FOR THE TREATMENT OF CANCER

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Page/Page column 41-42, (2011/04/18)

The present invention includes novel compound and methods of treating a disease or disorder by antagonizing Bcl-2 family proteins, particularly compounds of Formula (I) or pharmaceutically acceptable salt thereof, as well as methods of treating a disease,

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