64806-53-7

Upstream product

• 62762-20-3 1-phenylthio-1-trimethylsilylethene 
• 1822-73-7 phenylthioethylene 
• 108-98-5 thiophenol 
• 5535-49-9 2-Chloroethyl phenyl sulfide 

Downstream Products

• 107967-52-2 5-(2-Benzenesulfinyl-ethyl)-2-phenyl-3a,4,7,7a-tetrahydro-isoindole-1,3-dione 
• 107967-51-1 (1S,2R)-4-(2-Benzenesulfinyl-ethyl)-cyclohex-4-ene-1,2-dicarboxylic acid dimethyl ester 
• 107967-50-0 4-(2-Benzenesulfinyl-ethyl)-cyclohexa-1,4-diene-1,2-dicarboxylic acid dimethyl ester 
• 107967-56-6 3-(2-Benzenesulfinyl-ethyl)-cyclohex-3-enecarboxylic acid methyl ester 
• 107967-55-5 4-(2-Benzenesulfinyl-ethyl)-cyclohex-3-enecarboxylic acid methyl ester 
• 107967-53-3 1-[4-(2-Benzenesulfinyl-ethyl)-cyclohex-3-enyl]-ethanone 
• 107967-54-4 1-[3-(2-Benzenesulfinyl-ethyl)-cyclohex-3-enyl]-ethanone 
• 107967-58-8 3-(2-Benzenesulfinyl-ethyl)-cyclohex-3-enecarbaldehyde 
• 107967-57-7 4-(2-Benzenesulfinyl-ethyl)-cyclohex-3-enecarbaldehyde 
• 107967-49-7 3-methylene-5-phenylsulfinyl-1-pentene 
• 120395-17-7 C₂₁H₁₈OS 

Relevant academic research and scientific papers

New method for the synthesis of indenes

A new two-step method was developed for the synthesis of 2-sulfonyl-substituted indenes from aromatic aldehydes. The reactions of 1-phenylsulfonyl-1-(trimethylsilyl)ethylene with ortho-lithiated derivatives of aromatic and heteroaromatic aldehydes afford conjugate addition products whose subsequent cyclization gives substituted 2-sulfonylindenes in preparative yields. The reactions of 2-(phenylsulfonyl)indenes with Grignard reagents were studied. It was shown that the sulfonyl group can be replaced in the presence of iron(III) acetylacetonate.

A Michael Addition and Peterson Olefination Sequence Using 1-Silylethenyl Sulfides and Sulfoxide

Reaction of organolithiums with a 1-(trimethylsilyl)ethenyl sulfide produces 1,2-bis(trimethylsilyl)-cyclopropanes, while use of 1-silylethenyl sulfides bearing a bulkier silyl moiety results in exclusive formation of the corresponding Michael adducts anions which are then quenched with aldehydes to give vinyl sulfides.On the contrary, a 1-(trimethylsilyl)ethenyl sulfoxide undergoes smooth Michael addition with a variety of organometallics and the resulting carbanion intermediates can be quenched with aldehydes to produce vinyl sulfoxides.Scope and limitations of these sequential reactions are discussed.