64839-18-5

Upstream product

• 20548-02-1 (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexan-1-one 
• 108-24-7 acetic anhydride 

Downstream Products

• 20107-09-9 (2S,4S)-4-acetoxy-2-bromo-2,6,6-trimethylcyclohexanone 
• 70905-65-6 1(R),4(S),5(R)-4-ethynyl-4-hydroxy-3,3,5-trimethyl-cyclohexyl acetate 
• 118829-40-6 (R)-4-ethynyl-3,5,5-trimethylcyclohex-3-en-1-ol 
• 76530-42-2 (R)-4-ethynyl-3,5,5-trimethylcyclohex-3-enyl acetate 
• 118829-47-3 1-<4-(1-methoxy-1-methylethoxy)-2,6,6-trimethylcyclohex-1-enyl>-3-methylpenta-1,4-dien-3-ol 
• 64809-42-3 (Z)-5-((S)-4-Hydroxy-2,6,6-trimethyl-3-oxo-cyclohex-1-enyl)-3-methyl-pent-2-en-4-ynal 
• 64809-44-5 Phenoxy-acetic acid (S)-3,5,5-trimethyl-4-((1E,3Z)-3-methyl-5-oxo-penta-1,3-dienyl)-2-oxo-cyclohex-3-enyl ester 
• 69297-10-5 Phenoxy-acetic acid (S)-4-((1Z,3E)-5-bromo-3-methyl-penta-1,3-dienyl)-3,5,5-trimethyl-2-oxo-cyclohex-3-enyl ester 
• 69350-54-5 Phenoxy-acetic acid (S)-4-((1Z,3E)-5-hydroxy-3-methyl-penta-1,3-dienyl)-3,5,5-trimethyl-2-oxo-cyclohex-3-enyl ester 
• 64809-43-4 (2Z,4E)-5-((S)-4-Hydroxy-2,6,6-trimethyl-3-oxo-cyclohex-1-enyl)-3-methyl-penta-2,4-dienal 
• 64839-28-7 (2E,4E)-5-[(4S)-4-Hydroxy-2,6,6-trimethyl-3-oxocyclohex-1-enyl]-3-methylpenta-2,4-dienal 
• 69350-38-5 (1R,4S)-1-((Z)-5-Hydroxy-3-methyl-pent-3-en-1-ynyl)-2,6,6-trimethyl-cyclohex-2-ene-1,4-diol 
• 69350-37-4 (1S,4S)-1-((Z)-5-Hydroxy-3-methyl-pent-3-en-1-ynyl)-2,6,6-trimethyl-cyclohex-2-ene-1,4-diol 
• 64839-19-6 4(S)-2,6,6-trimethyl-4-acetoxy-cyclohex-2-en-1-one 

Relevant academic research and scientific papers

88. Technical Procedures for the Syntheses of Carotenoids and Related Compounds from 6-Oxo-isophorone: Syntheses of (3R,3'R)-Zeaxanthin

Starting from the readily available, optically active (4R)-hydroxy-2,2,6-trimethylcyclohexanone (2), a new technical synthesis of (3R,3'R)-zeaxanthin is described.According to a completely new C9 + C2 + C4= C15 scheme, the ketone 2 was protected, ethynyla

Total synthesis of C31-methyl ketone apocarotenoids 3. On the structure of hopkinsiaxanthin: First total synthesis of (all-E)-(3S)- and (9Z)-(3S)-7′-apohopkinsiaxanthin

Optically active (all-E)-(3S)-7′-apohopkinsiaxanthin, previously known as F1, and (9Z)-(3S)-7′-apohopkinsiaxanthin have been prepared by total synthesis for the first time in ca. 1% combined overall yield, including two unidentified geometrical isomers, in sixteen linear steps from (4R,6R)-actinol, (2E)-3-methyl-2-penten-4-yn-1-ol, (7-formyl-2-methyl-2,4,6-octatrienyl)triphenylphosphonium bromide, (3-formyl-2-butenyl)triphenylphosphonium bromide and methyllithium, by use of a C15+C10+C5+C1 approach. By an alternative route from (2Z)-5-[((4S)-4-hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexenyl)-3-methyl-2-penten- 4-ynyl]triphenylphosphonium bromide, (7-formyl-2-methyl-2,4,6-octatrienyl)triphenylphosphonium bromide and (2E)-3-methyl-4-oxo-2-pentenal, the same target compounds were obtained in a combined overall yield of >61%, including four unidentified geometrical isomers, over two steps, by use of a C15+C16 approach. A hypothetical structure for hopkinsiaxanthin is discussed, based on present and previously reported spectroscopic and chemical data for (all-E)-(3S)- and (9Z)-(3S)-7′-apohopkinsiaxanthin and on data previously reported for hopkinsiaxanthin itself. Acta Chemica Scandinavica 1997.