648425-39-2Relevant academic research and scientific papers
Novel halogenated arylvinyl-1,2,4 trioxanes as potent antiplasmodial as well as anticancer agents: Synthesis, bioevaluation, structure-activity relationship and in-silico studies
Agrawal, Prakhar,Chaudhary, Sandeep,Coghi, Paolo,Congling, Qiu,Sahal, Dinkar,Tiwari, Mohit K.,Wai Wong, Vincent Kam,Yadav, Dharmendra K.,Yang, Li Jun
, (2021/07/28)
Herein, we have synthesized a series of lipophilic, halogenated-arylvinyl-1,2,4-trioxanes 8a–g (28 compounds) and assessed for their in vitro anti-plasmodial activity in Plasmodium falciparum culture using SYBRgreen-I fluorescence assay against chloroquin
Synthesis of novel diazatricyclodecanes (DTDs). Effects of structural variation at the C3′ allyl end and at the phenyl ring of the cinnamyl chain on μ-receptor affinity and opioid antinociception
Pinna, Gerard Aime,Cignarella, Giorgio,Ruiu, Stefania,Loriga, Giovanni,Murineddu, Gabriele,Villa, Stefania,Grella, Giuseppe Enrico,Cossu, Gregorio,Fratta, Walter
, p. 4015 - 4026 (2007/10/03)
Two series of analogues of 9-propionyl-10-cinnamyl-9,10-diazatricyclo[4.2.1.12,5]decane (1a) and 2-propionyl-7-cinnamyl-2,7-diazatricyclo[4.4.0.03,8]decane (2a), in which the cinnamyl moiety was replaced by various aralkenyl chains,
