648440-50-0Relevant academic research and scientific papers
Design and synthesis of amidoxime derivatives for orally potent C-alkylamidine-based antimalarial agents
Ouattara, Mahama,Wein, Sharon,Denoyelle, Severine,Ortial, Stephanie,Durand, Thierry,Escale, Roger,Vial, Henri,Vo-Hoang, Yen
, p. 624 - 626 (2009)
Within the frame of the design of prodrug candidates to deliver a C-alkylamidine antimalarial agent, we showed that specific O-substitutions were needed on the alkylamidoxime structure. Among the newly synthesized molecules, bis-oxadiazolone and bis-O-met
Compounds with antiparasitic activity and medicines containing same
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, (2008/06/13)
The invention relates to compounds having an anti-parasitic, in particular antimalarial activity, characterized in that they correspond to general formula (I) Applications in particular as compounds with anti-parasitic activity.
