64880-98-4Relevant academic research and scientific papers
Thiophenol-mediated improvement of the Pictet-Spengler cyclization of N-tosyl-β-phenethylamines with aldehydes
Silveira, Claudio C.,Vieira, Adriano S.,Kaufman, Teodoro S.
, p. 7545 - 7549 (2006)
The Lewis acid-catalyzed Pictet-Spengler condensation of N-tosyl-β-phenethylamines with aldehydes is improved by the addition of thiophenol, furnishing better yields of 1-substituted tetrahydroisoquinolines at a given time.
