648883-76-5Relevant academic research and scientific papers
Total synthesis of (+)-13-deoxytedanolide
Smith III, Amos B.,Adams, Christopher M.,Lodise Barbosa, Stephanie A.,Degnan, Andrew P.
, p. 350 - 351 (2003)
In this communication we describe the first total synthesis of (+)-13-deoxytedanolide, an architecturally complex marine macrolide possessing significant antitumor activity. The cornerstone of the synthesis comprises a highly convergent dithiane coupling
Total synthesis and stereochemical assignment of myriaporones 1, 3, and 4
Fleming, Kristen N.,Taylor, Richard E.
, p. 1728 - 1730 (2007/10/03)
Two stereoselective aldol reactions, a nitrile oxide cycloaddition, and a stereoselective late-stage epoxidation were key steps in the total synthesis of myriaporones 1, 3, and 4 (see scheme). The synthesis allowed the unambiguous assignment of stereogeni
