777096-35-2

Upstream product

• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 
• 777096-34-1 C₆₈H₁₂₆O₁₀S₂Si₃ 
• 777096-55-6 Acetic acid (E)-(2S,3S,4R,5R,6S,7R,10S)-10-[1,3]dithian-2-yl-3-methoxy-5-(4-methoxy-benzyloxy)-4,6,8-trimethyl-7-triisopropylsilanyloxy-2-(2-trimethylsilanyl-ethoxymethoxy)-undec-8-enyl ester 
• 497056-67-4 (E)-(2S,3S,4R,5R,6S,7R,10S)-10-[1,3]Dithian-2-yl-3-methoxy-5-(4-methoxy-benzyloxy)-4,6,8-trimethyl-7-triisopropylsilanyloxy-2-(2-trimethylsilanyl-ethoxymethoxy)-undec-8-en-1-ol 
• 777096-54-5 Acetic acid (E)-(2S,3S,4R,5R,6S,7R,10S)-10-[1,3]dithian-2-yl-2-hydroxy-3-methoxy-5-(4-methoxy-benzyloxy)-4,6,8-trimethyl-7-triisopropylsilanyloxy-undec-8-enyl ester 
• 251083-06-4 {(E)-(1R,4S)-1-[(1S,2R,3R,4S)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-4-methoxy-2-(4-methoxy-benzyloxy)-1,3-dimethyl-butyl]-4-[1,3]dithian-2-yl-2-methyl-pent-2-enyloxy}-triisopropyl-silane 
• 777096-29-4 (E)-(2S,3S,4R,5R,6S,7R,10S)-10-[1,3]Dithian-2-yl-3-methoxy-5-(4-methoxy-benzyloxy)-4,6,8-trimethyl-7-triisopropylsilanyloxy-undec-8-ene-1,2-diol 
• 777096-24-9 (S)-4-Benzyl-3-[(E)-(2S,3S,6R)-3-(diethyl-isopropyl-silanyloxy)-7-(4-methoxy-benzyloxy)-4,6-dimethyl-2-vinyl-hept-4-enoyl]-oxazolidin-2-one 
• 777096-47-6 Acetic acid (R)-3-{(4R,5S)-5-[(E)-(1S,4R)-1-(diethyl-isopropyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4-dimethyl-pent-2-enyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-butyl ester 
• 777096-27-2 (R)-3-{(4R,5S)-5-[(E)-(1S,4R)-1-(Diethyl-isopropyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4-dimethyl-pent-2-enyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-butan-1-ol 
• 497056-64-1 Acetic acid (E)-(2S,3S,6R)-3-(diethyl-isopropyl-silanyloxy)-2-((1R,2R)-1-hydroxy-2-methyl-but-3-enyl)-7-(4-methoxy-benzyloxy)-4,6-dimethyl-hept-4-enyl ester 
• 777096-26-1 [(E)-(1S,4R)-1-[(4R,5S)-2,2-Dimethyl-4-((R)-1-methyl-allyl)-[1,3]dioxan-5-yl]-5-(4-methoxy-benzyloxy)-2,4-dimethyl-pent-2-enyloxy]-diethyl-isopropyl-silane 
• 497056-62-9 (S)-4-Benzyl-3-[(E)-(2S,3S,6R)-3-hydroxy-7-(4-methoxy-benzyloxy)-4,6-dimethyl-2-vinyl-hept-4-enoyl]-oxazolidin-2-one 
• 777096-46-5 (2S,3R,4R)-2-[(E)-(1S,4R)-1-(Diethyl-isopropyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4-dimethyl-pent-2-enyl]-4-methyl-hex-5-ene-1,3-diol 

Downstream Products

• 497056-70-9 10-hydroxy-11-(1-hydroxy-2,4-dimethyl-hepta-2,5-dienyl)-16-methoxy-18-(4-methoxy-benzyloxy)-9,17,19,21,23-pentamethyl-20-triisopropylsilanyloxy-15-(2-trimethylsilanyl-ethoxymethoxy)-13-oxa-1,5-dithia-spiro[5.17]tricos-21-en-14-one 
• 497056-73-2 10-[2-(4,6-dihydroxy-5-hydroxymethyl-3,7,9-trimethyl-dodeca-7,10-dienyl)-[1,3]dithian-2-yl]-3-methoxy-5-(4-methoxy-benzyloxy)-4,6,8-trimethyl-7-triisopropylsilanyloxy-2-(2-trimethylsilanyl-ethoxymethoxy)-undec-8-enoic acid 
• 777096-58-9 11-(2,4-dimethyl-1-triethylsilanyloxy-hepta-2,5-dienyl)-10-hydroxy-16-methoxy-18-(4-methoxy-benzyloxy)-9,17,19,21,23-pentamethyl-20-triisopropylsilanyloxy-15-(2-trimethylsilanyl-ethoxymethoxy)-13-oxa-1,5-dithia-spiro[5.17]tricos-21-en-14-one 
• 777096-57-8 C₆₇H₁₂₂O₁₂S₂Si₂ 

Relevant academic research and scientific papers

Total synthesis of (+)-13-deoxytedanolide

In this communication we describe the first total synthesis of (+)-13-deoxytedanolide, an architecturally complex marine macrolide possessing significant antitumor activity. The cornerstone of the synthesis comprises a highly convergent dithiane coupling