64890-06-8

Usage

Uses

Used in Pharmaceutical and Medicinal Chemistry:
7-Nitro-2-phenyl-1H-indole is used as a pharmaceutical intermediate for the synthesis of various organic compounds and drugs. Its unique structure and properties make it a promising candidate for the development of new pharmaceuticals.
Used in Research and Biological Imaging:
7-Nitro-2-phenyl-1H-indole is used as a fluorescent probe in the field of research and biological imaging. Its fluorescent properties allow for the visualization and tracking of biological processes and molecules, making it a valuable tool in scientific studies.

Upstream product

• 5667-47-0 phenacyldimethylsulfonium bromide 
• 88-74-4 2-nitro-aniline 
• 536-74-3 phenylacetylene 
• 603-85-0 2-Amino-3-nitrophenol 
• 812646-99-4 N-(2'-hydroxy-6'-nitrophenyl)trifluoroacetamide 
• 500992-09-6 N-[(6'-nitro-2'-phenylethynyl)phenyl]butyramide 

Downstream Products

• 500992-15-4 2-Phenyl-1H-indol-7-amine 
• 1253395-99-1 N-(3-formyl-2-phenylindol-7-yl)-4-methoxybenzenesulfonamide 
• 1253396-00-7 N-(3-hydroxymethyl-2-phenylindol-7-yl)-4-methoxybenzenesulfonamide 
• 870820-07-8 N-(2-phenylindol-7-yl)-4-toluenesulfonamide 
• 1253396-01-8 3-chloro-7-nitro-2-phenylindole 
• 870820-08-9 N-(2-phenylindol-7-yl)-4-methoxybenzenesulfonamide 
• 1253395-95-7 N-(3-chloro-2-phenylindol-7-yl)-4-methoxybenzenesulfonamide 
• 1253395-96-8 N-(3-piperidinomethyl-2-phenylindol-7-yl)-4-methoxybenzenesulfonamide 
• 1253395-98-0 N-[3-(4-morpholino)methyl-2-phenylindol-7-yl]-4-methoxybenzenesulfonamide 

Relevant academic research and scientific papers

Synthesis of anti-microtubule N-(2-arylindol-7-yl)-benzenesulfonamide derivatives and their antitumor mechanisms

Breaking the cycle: A series of N-(2-arylindol-7-yl)benzenesulfonamide derivatives were prepared. Among them, compound 2 showed promising antiproliferative activity against hormone-resistant prostate cancer PC-3 cells, induced G2/M-phase arrest

Stepwise and one-pot cross-coupling-heteroannulation approaches toward 2-substituted C5-, C6-, and C7-nitroindoles

A general and efficient synthesis of 2-substituted C5-, C6-, and C7-nitroindoles has been established. Starting from commercially available 2-amino nitrophenols, C5-, C6-, and C7-nitroindoles were synthesized via the stepwise Pd-catalyzed cross-coupling o

Chemistry of aminophenols. Part 2: A general and efficient synthesis of indoles possessing a nitrogen substituent at the C4, C5, C6, and C7 positions

A general and efficient synthesis of indoles possessing a nitrogen substituent at the C4, C5, C6, and C7 positions has been developed. Starting from commercially available nitro 2-aminophenols, 5-, 6-, and 7-arenesulfamoylindoles were synthesized via a ba