64890-22-8

Basic information

• Product Name: 4-Pyridinamine, N-methyl-N-phenyl-
• CAS NO: 64890-22-8
• Molecular Formula: C12H12N2
• Molecular Weight: 184.241
• Mol File: 64890-22-8.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: 4-Pyridinamine, N-methyl-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinamine, N-methyl-N-phenyl-(64890-22-8)
• EPA Substance Registry System: 4-Pyridinamine, N-methyl-N-phenyl-(64890-22-8)

Safety Data

• Hazardous Substances Data: 64890-22-8(Hazardous Substances Data)

Upstream product

• 4783-86-2 4-phenoxypyridine 
• 2739-12-0 N-methylaniline hydrochloride 
• 7379-35-3 4-chlorpyridine hydrochloride 
• 100-61-8 N-methylaniline 
• 109-00-2 3-HYDROXYPYRIDINE 
• 1413439-93-6 C₉H₁₂N₂O₂ 
• 1413439-80-1 C₁₂H₂₀N₂O₂Si 
• 1120-87-2 4-bromopyridin 
• 626-61-9 4-Chloropyridine 
• 504-24-5 4-aminopyridine 
• 872-85-5 pyridine-4-carbaldehyde 
• 620-08-6 4-methoxypyridine 
• 71366-41-1 4'-Oxo-4'H-[1,1']bipyridinyl-1-ylium; chloride 
• 100-48-1 pyridine-4-carbonitrile 

Relevant articles and documents

Diffusion Control in Single-Site Zinc Reticular Amination Catalysts

Zn-containing metal-organic frameworks have been used for the first time as heterogeneous catalysts in the amination of C-Cl bonds. The use of extended bis(pyrazolate) linkers can generate highly porous architectures, which favor the diffusion of amines t

Metal-free, redox-neutral, site-selective access to heteroarylamine via direct radical?radical cross-coupling powered by visible light photocatalysis

Transition-metal-catalyzed C?N bond-forming reactions have emerged as fundamental and powerful tools to construct arylamines, a common structure found in drug agents, natural products, and fine chemicals. Reported herein is an alternative access to heteroarylamine via radical?radical cross-coupling pathway, powered by visible light catalysis without any aid of external oxidant and reductant. Only by visible light irradiation of a photocatalyst, such as a metal-free photocatalyst, does the cascade single-electron transfer event for amines and heteroaryl nitriles occur, demonstrated by steady-state and transient spectroscopic studies, resulting in an amine radical cation and aryl radical anion in situ for C?N bond formation. The metal-free and redox economic nature, high efficiency, and site-selectivity of C?N cross-coupling of a range of available amines, hydroxylamines, and hydrazines with heteroaryl nitriles make this protocol promising in both academic and industrial settings.

Anticancer-Active N-Heteroaryl Amines Syntheses: Nucleophilic Amination of N-Heteroaryl Alkyl Ethers with Amines

A mild amination protocol of N-heteroaryl alkyl ethers with various amines is described. This transformation is achieved by utilizing simple and readily available base as promoter via C-O bond cleavage, offering a new amination strategy to access several anticancer-active compounds. This work is highlighted by the excellent functional group compatibility, scalability, wide substrate scope, and easy derivatization of a variety of drugs.