648905-09-3

Upstream product

• 1152501-48-8 C₆H₆BrClN₂O₂S 
• 74-88-4 methyl iodide 
• 60811-21-4 1-bromo-3-chloro-4-fluorobenzene 
• 101084-82-6 4-bromo-2-chloro-1-(methylsulfanyl)benzene 

Downstream Products

• 648905-10-6 1-(2-{4-[2-(3-chloro-4-methanesulfonyl-phenyl)-6-methoxy-naphthalen-1-yloxy]-phenoxy}-ethyl)-piperidine 
• 1034822-81-5 tert-butyl 1'-[3-chloro-4-(methylsulfonyl)phenyl]-4-4'-bipiperidine-1-carboxylate 
• 877132-13-3 3-(3-chloro-4-methanesulfonyl-phenyl)-1-cyclopentyl-propan-1-one 
• 945619-15-8 C₂₂H₂₅ClO₆S 

Relevant academic research and scientific papers

NOVEL IMIDAZOLIDINE-2,4-DIONE DERIVATIVES

A subject of the present application is novel imidazolidine-2,4-dione derivatives of formula (I). These products have an anti-proliferative activity. They are particularly useful for treating the pathological states and the diseases linked to an abnormal cell proliferation such as cancers. The invention also relates to the pharmaceutical compositions containing said products and their use for the preparation of a medicament.

NEW PYRIMIDINE DERIVATIVES AND THEIR USE IN THERAPY AS WELL AS THE USE OF PYRIMIDINE DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR PREVENTION AND/OR TREATMENT OF ALZHEIMER’S DISEASE

The present invention relates to use of compounds of formula (I) as a free base or a pharmaceutically acceptable salt, solvate or solvate of salt thereof, a process for their preparation and new intermediates used therein, as pharmaceutical ingredients fo

INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME

The present invention provides compounds of formula (4), and their pharmaceutically acceptable salts and solvates, which are useful as inhibitors of the Hepatitis C virus (HCV) polymerase enzyme and are also useful for the treatment of HCV infections in HCV-infected mammals. The present invention also provides pharmaceutical compositions comprising compounds of formula (4), their pharmaceutically acceptable salts and solvates. Furthermore, the present invention provides intermediate compounds and methods useful in the preparation of compounds of formula (4).

SELECTIVE ESTROGEN RECEPTOR MODULATORS CONTAINING A PHENYLSULFONYL GROUP

The present invention relates to a selective estrogen receptor modulator of formula I or a pharmaceutical acid addition salt thereof; useful, e.g., for treating endometriosis and/or uterine leiomyoma/leiomyomata.