648909-27-7Relevant academic research and scientific papers
A concise total synthesis of (-)-dehydroclausenamide utilizing the novel formation of cis-epoxide as the key step
Yan, Zhaohua,Wang, Jianqiang,Tian, Weisheng
, p. 9383 - 9384 (2007/10/03)
The asymmetric total synthesis of (-)-dehydroclausenamide 1 was accomplished through a concise and efficient synthetic route employing as the key step the novel formation of cis-epoxy amide 7, which was resulted from the reaction of starting material 4 bearing an optically pure erythro vicinal diol unit with 5H-3-oxa-octafluoro pentanesulfonyl fluoride (HCF2CF 2OCF2CF2SO2F) in the presence of 1,8-diazabicyclo[5.4.0]-7-undecene (DBU).
