Cas 648929-25-3,(R)-[3-(cyclopropyloxy)-4-(difluoromethoxy)phenyl]{2-[2,2,2-trifluoro-1-(methoxymethoxy)-1-(trifluoromethyl)ethyl]-1,3-thiazol-5-yl}methanol

648929-25-3

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Basic information

Product Name: (R)-[3-(cyclopropyloxy)-4-(difluoromethoxy)phenyl]{2-[2,2,2-trifluoro-1-(methoxymethoxy)-1-(trifluoromethyl)ethyl]-1,3-thiazol-5-yl}methanol
Synonyms: (R)-[3-(cyclopropyloxy)-4-(difluoromethoxy)phenyl]{2-[2,2,2-trifluoro-1-(methoxymethoxy)-1-(trifluoromethyl)ethyl]-1,3-thiazol-5-yl}methanol
CAS NO:648929-25-3
Molecular Formula:
Molecular Weight: 523.401
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (R)-[3-(cyclopropyloxy)-4-(difluoromethoxy)phenyl]{2-[2,2,2-trifluoro-1-(methoxymethoxy)-1-(trifluoromethyl)ethyl]-1,3-thiazol-5-yl}methanol(CAS DataBase Reference)
NIST Chemistry Reference: (R)-[3-(cyclopropyloxy)-4-(difluoromethoxy)phenyl]{2-[2,2,2-trifluoro-1-(methoxymethoxy)-1-(trifluoromethyl)ethyl]-1,3-thiazol-5-yl}methanol(648929-25-3)
EPA Substance Registry System: (R)-[3-(cyclopropyloxy)-4-(difluoromethoxy)phenyl]{2-[2,2,2-trifluoro-1-(methoxymethoxy)-1-(trifluoromethyl)ethyl]-1,3-thiazol-5-yl}methanol(648929-25-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 648929-25-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 648929-25-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,8,9,2 and 9 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 648929-25:
(8*6)+(7*4)+(6*8)+(5*9)+(4*2)+(3*9)+(2*2)+(1*5)=213
213 % 10 = 3
So 648929-25-3 is a valid CAS Registry Number.

648929-25-3Upstream product

648929-16-2 [3-(cyclopropyloxy)-4-(difluoromethoxy)phenyl]{2-[2,2,2-trifluoro-1-(methoxymethoxy)-1-(trifluoromethyl)ethyl]-1,3-thiazol-5-yl}methanone

648929-25-3Downstream Products

648929-25-3Relevant academic research and scientific papers

Highly Enantioselective Hydrogenation of Aromatic-Heteroaromatic Ketones

Chen, Cheng-Yi,Reamer, Robert A.,Chilenski, Jennifer R.,McWilliams, Chris J.

, p. 5039 - 5042 (2003)

(Equation presented) Asymmetric hydrogenation of ketone 1 using trans-RuCl2[(R)-xylbinap][(R)-daipen] (3) as a catalyst afforded secondary alcohol 2 quantitatively and in 99.4% ee. Further exploration of the effect of the thiazole ring substitution revealed that the catalyst was highly effective for the enantioselective hydrogenation of 5-benzoyl thiazoles, which afforded corresponding alcohols in 92-99% ee. The same protocol was applicable to a variety of aromatic-heteroaromatic ketones to generate secondary alcohols in excellent enantioselectivities.

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