64919-15-9

Basic information

• Product Name: LAURIC ACID 2-CHLOROETHYL ESTER
• Synonyms: LAURIC ACID 2-CHLOROETHYL ESTER;LABOTEST-BB LT00000096;2-CHLOROETHYL LAURATE;Lauric acid beta-chloroethyl ester;Lauricacidchloroethylester;Lauricacid2-chloroethylester(beta-);Dodecanoic acid 2-chloroethyl ester;2-chloroethyl dodecanoate
• CAS NO: 64919-15-9
• Molecular Formula: C₁₄H₂₇ClO₂
• Molecular Weight: 262.82
• Mol File: 64919-15-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 187 °C / 10mmHg
• Flash Point: 156.6°C
• Appearance: /
• Density: 0.96
• Vapor Pressure: 0.000117mmHg at 25°C
• Refractive Index: 1.4460-1.4500
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: LAURIC ACID 2-CHLOROETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: LAURIC ACID 2-CHLOROETHYL ESTER(64919-15-9)
• EPA Substance Registry System: LAURIC ACID 2-CHLOROETHYL ESTER(64919-15-9)

Safety Data

• Hazardous Substances Data: 64919-15-9(Hazardous Substances Data)

Usage

General Description

LAURIC ACID 2-CHLOROETHYL ESTER is a chemical compound that is commonly used as a raw material for the production of various surfactants and pharmaceuticals. It is derived from lauric acid, a saturated fatty acid commonly found in coconut oil and palm kernel oil. The 2-chloroethyl ester group adds a chloroethyl functional group to the lauric acid molecule, making it useful for a wide range of applications in the chemical industry. It is known for its surfactant properties, making it suitable for use in cleaning products and personal care items. Additionally, it can also be used in the synthesis of pharmaceutical compounds for various medicinal purposes.

InChI:InChI=1/C14H27ClO2/c1-2-3-4-5-6-7-8-9-10-11-14(16)17-13-12-15/h2-13H2,1H3

Upstream product

• 629-25-4 Sodium laurate 
• 107-06-2 1,2-dichloro-ethane 
• 143-07-7 lauric acid 
• 107-07-3 2-chloro-ethanol 
• 112-16-3 n-dodecanoyl chloride 
• 71071-51-7 2,2,2-Trichloroethyl dodecanoate 

Downstream Products

• 25234-60-0 (2-lauroyloxy-ethyl)-trimethyl-ammonium; chloride 
• 143-07-7 lauric acid 
• 301-11-1 1-lauroyloxy-2-thiocyanato-ethane 

Relevant articles and documents

Zinc-catalyzed depolymerization of polyethers to produce valuable building blocks

The recycling of polymers continues to be a significant matter for a sustainable society. In particular, the conversion of end-of-life polymers to monomers or suitable low-molecular weight chemicals creates a feedstock for new high-quality polymeric materials and contributes to conserve resources and allow overall an efficient waste-managing system. In the present study, we have set up a straightforward methodology for the depolymerization of artificial polyethers applying cheap and abundant zinc( II) salts as precatalysts. In the presence of bio-based fatty acid chlorides as depolymerization reagent well-defined chloroesters were accessible in good to excellent yields. Moreover, acetic anhydride and fatty acids were applied as depolymerization reagents resulting in the formation of diacetates in moderate yields. In both cases the obtained products (chloroesters, diacetates) can be useful building blocks in polymerization chemistry. Noteworthy, overall a recycling of polyethers are possible. Springer Science+Business Media New York 2014.

Gemini pyridinium surfactants: Synthesis and their surface active properties

New pyridinium Gemini surfactants have been synthesized by esterification of renewable fatty acids with halogenated alcohols furnishing respective esters (2-chloroethyl hexadecanoate, 2-chloroethyl tetradecanoate, 2-chloroethyl dodecanoate, 2-bromoethyl hexadecanoate, 2-bromoethyl tetradecanoate and 2-bromoethyl dodecanoate) followed by their subsequent treatment with 4,4′-trimethylenedipyridine resulting into the formation of title Gemini surfactants: (4,4′-(propane-1,3-diyl)bis(1-(2-(hexadecanoyl oxy) ethyl) dipyridinium chloride(7), (4,4′-(propane-1,3-diyl)bis(1-(2-(tetradecanoyl oxy) ethyl) dipyridinium chloride (8), 4,4′-(propane-1,3-diyl)bis(1-(2- (dodecanoyl oxy) ethyl) dipyridinium chloride (9), (4,4′-(propane-1,3- diyl)bis(1-(2-(hexadecanoyl oxy) ethyl) dipyridinium bromide (10), (4,4′-(propane-1,3-diyl)bis(1-(2-(tetradecanoyl oxy) ethyl) dipyridinium bromide (11), 4,4′-(propane-1,3-diyl)bis(1-(2-(dodecanoyl oxy) ethyl) dipyridinium bromide (12). Their identifications are based on IR, 1H-, 13C-NMR, DEPT, COSY and mass spectral studies. Their surface active properties are also evaluated on the basis of surface tension and conductivity measurements and thermal stability of these long chain cationics Gemini surfactants have been measured by thermal gravimetric analysis under nitrogen atmosphere.

Sustained release pharmaceutical compositions

The present invention relates to a pharmaceutical composition comprising a salt of quaternary ammonium of an acid drug in the form of a suspension or an emulsion, suitable for parenteral administration and providing a sustained release of the drug. In one preferred embodiment, the present invention is directed to a long term sustained release composition for parenteral administration, comprising a salt of heparin or low molecular weight heparin in an emulsion with a salt of acylcholine, for the prevention and treatment of venous thrombosis and pulmonary embolism.