6493-80-7Relevant academic research and scientific papers
New entry to the enantioselective formation of substituted cyclohexenes bearing an all-carbon quaternary stereogenic center
Komine, Keita,Urayama, Yasuhiro,Hosaka, Taku,Fukuda, Hayato,Hatakeyama, Susumi,Ishihara, Jun
supporting information, p. 273 - 281 (2020/02/04)
Enantioselective formation of cyclohexene derivatives bearing an all-carbon quaternary stereogenic center is described. The racemic cyclohexenes are readily transformed to chiral substituted cyclohexenes in good yield with excellent enantioselectivity and diastereoselectivity by a palladium-mediated deracemization. The resulting products are promising synthetic intermediates of biologically active natural products. This protocol provides us with a new entry to the concise and scalable synthesis of multifunctionalized compounds.
Studies towards the synthesis of coprinolone, Δ6- coprinolone, and radulone A via an anionic electrocyclization cascade
Lawrence, Andrew L.,Lee, Victor,Adlington, Robert M.
scheme or table, p. 2087 - 2088 (2009/04/07)
Studies towards the synthesis of coprinolone, Δ6- coprinolone, and radulone A, resulting in the synthesis of an advanced intermediate with the tricyclic protoilludane carbon skeleton, are described. Georg Thieme Verlag Stuttgart.
Enones with Strained Double Bonds. 8. The Bicyclooctane Systems
House, Herbert O.,Haack, John L.,McDaniel, William C.,VanDerveer, Don
, p. 1643 - 1654 (2007/10/02)
The bicyclic enones bicyclooct-1-en-3-one (4) and 1-methylbicyclooct-5(6)-en-7-one (5) have been generated from various precursors and trapped by the addition of nucleophiles such as MeOH, PhSeH, or H2O.The bridgehead enone 5 has also been trapped as its cycloadduct 31 with furan.Pyrolysis of this cycloadduct 31 reformed the bridgehead enone 5 that was trapped as the cycloadduct 32.Related bridgehead enones 35 and 47 have also been generated as intermediates leading to products with bridgehead methoxy substituents.
