649551-06-4

Basic information

• Product Name: JNJ-17156516
• Synonyms: JNJ-17156516
• CAS NO: 649551-06-4
• Molecular Weight: 481.378
• Mol File: 649551-06-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: JNJ-17156516(CAS DataBase Reference)
• NIST Chemistry Reference: JNJ-17156516(649551-06-4)
• EPA Substance Registry System: JNJ-17156516(649551-06-4)

Safety Data

• Hazardous Substances Data: 649551-06-4(Hazardous Substances Data)

Upstream product

• 648869-66-3 3-[5-(3,4-dichlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl]-2-m-tolyl propionic acid ethyl ester 
• 648861-60-3 3-[5-(3,4-Dichloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-2-m-tolyl-propionic acid 
• 648869-63-0 (S)-3-[5-(3,4-dichloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-2-m-tolyl-propionic acid (S)-1-ethoxycarbonyl-ethyl ester 
• 957127-47-8 C₃₁H₃₀Cl₂N₂O₅ 
• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 

Downstream Products

• 648861-58-9 sodium (S)-3-[5-(3,4-dichlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl]-2-m-tolyl propionate 
• 648869-44-7 (S)-N-(2-cyano-ethyl)-3-[5-(3,4-dichloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-2-m-tolyl-propionamide 

Relevant articles and documents

Design of concise, scalable route to a cholecystokinin 1 (CCK 1) receptor antagonist

(Chemical Equation Presented) Development of efficient, scalable routes for the synthesis of (S)-3-[5-(3,4-dichlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol- 3-yl]-2-m-tolyl propionic acid, a selective cholecystokinin 1 (CCK 1) receptor antagonist, is descri

CCK-1 RECEPTOR MODULATORS

There are provided by the present invention certain pyrazole based CCK-1 receptor modulators which have the general formula: (I) wherein Ar is an aromatic or heteroaromatic group, X is a hydrocarbon linker, Y is a bond or hydrocarbon linker and R1, R2, R3, R4 and R5 are certain organic substituents, and methods of making the same.