64957-64-8Relevant academic research and scientific papers
Synthesis of non-steroidal estrogen receptor antagonists R1128 A, B, C, and D via an oxazoline-promoted iterative ortho-lithiation strategy
Fukuda, Tsutomu,Fukushima, Koichiro,Sanai, Susumu,Iwao, Masatomo
, p. 133 - 135 (2012)
A concise total synthesis of non-steroidal estrogen receptor antagonists R1128 A-D (1a-1d) has been achieved using iterative ortho-lithiation of 2-(4-methoxyphenyl)-4,4- dimethyloxazoline (3) as the key reaction.
