64964-80-3Relevant articles and documents
Facile synthesis of coumaronochromones through palladium-catalyzed intramolecular cross dehydrogenative coupling
Gu, Chang-Xue,Liu, Jian-Guo,Chen, Wen-Wen,Xu, Ming-Hua
, (2021)
An efficient base-free palladium-catalyzed intramolecular cross dehydrogenative coupling of 2-aryloxy substituted 4-chromenones to access coumaronochromones has been achieved. A range of diversely substituted coumaronochromones can be facilely synthesized in good to excellent yields (up to 90%).
Oxidative regioselective amination of chromones exposes potent inhibitors of the hedgehog signaling pathway
Samanta, Rajarshi,Narayan, Rishikesh,Bauer, Jonathan O.,Strohmann, Carsten,Sievers, Sonja,Antonchick, Andrey P.
, p. 925 - 928 (2015/01/09)
A transition metal-free, oxidative, regioselective cross-coupling between non-functionalized azoles and chromones at C2-position was developed. A broad reaction scope and further transformation of products were demonstrated. The biological evaluation of products revealed a novel class of hedgehog signaling pathway inhibitors. This journal is