64972-07-2Relevant academic research and scientific papers
Investigation of the inhibitory effects of isoindoline-1,3-dion derivatives on hCA-I and hCA-II enzyme activities
Nadaroglu, Hayrunnisa,Gungor, Azize Alayl?,Gundogdu, ?zlem,Kishali, Nurhan Horasan,Sever, Belgin,Altintop, Mehlika Dilek
, p. 386 - 392 (2019)
Inhibition of carbonic anhydrase (CA) has emerged as a promising approach for the treatment of a variety of diseases such as glaucoma, epilepsy, obesity and cancer. As a result, the design of CA inhibitors (CAIs) is an outstanding field of medicinal chemi
Evaluation of xanthine oxidase inhibitor properties on isoindoline-1,3-dion derivatives and calculation of interaction mechanism
Gundu?du, ?zlem,Noma, Samir Abbas Ali,Taskin-Tok, Tugba,Ate?, Burhan,Kishali, Nurhan
, (2019/12/23)
The aim of the present study was to synthesis of isoindole-1,3(2H)-dione (Phthalimides) derivatives and to investigation the inhibition of xanthine oxidase (XO). In study, xanthine oxidase inhibitory activities of complexes were observed in the range from
Synthesis and anti-inflammatory activity of sulfonamides and carboxylates incorporating trimellitimides: Dual cyclooxygenase/carbonic anhydrase inhibitory actions
Abdel-Aziz, Alaa A.-M.,Angeli, Andrea,El-Azab, Adel S.,Hammouda, Mohammed E.A.,El-Sherbeny, Magda A.,Supuran, Claudiu T.
, p. 260 - 268 (2018/12/05)
Trimellitimides 6–21 were prepared and investigated in vivo for anti-inflammatory and ulcerogenic effects and in vitro for cytotoxicity. They were subjected to in vitro cyclooxygenase (COX-1/2) and carbonic anhydrase inhibition protocols. Compounds 6–11 a
