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2H-1,3,5-Oxadiazine-2,4,6(3H,5H)-trione, also known as 1,3,5-oxadiazine-4,6-dione, is a heterocyclic chemical compound with the molecular formula C3H2N2O3. It features an oxadiazine ring composed of two nitrogen atoms and one oxygen atom, and is recognized for its potential as a building block in organic synthesis and pharmaceutical research. 2H-1,3,5-Oxadiazine-2,4,6(3H,5H)-trione has garnered interest due to its possible biological activities, such as antibacterial and antifungal properties, and its utility as a scaffold in the design of new drug candidates in the field of medicinal chemistry.

6498-11-9

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6498-11-9 Usage

Uses

Used in Organic Synthesis:
2H-1,3,5-Oxadiazine-2,4,6(3H,5H)-trione is utilized as a key building block in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for the formation of diverse chemical entities, making it a valuable component in the synthesis of pharmaceuticals and other specialty chemicals.
Used in Pharmaceutical Research:
In Pharmaceutical Research, 2H-1,3,5-Oxadiazine-2,4,6(3H,5H)-trione serves as a scaffold for the design of new drug candidates. Its heterocyclic nature and potential biological activities make it a promising starting point for the development of novel therapeutic agents.
Used in Antibacterial Applications:
2H-1,3,5-Oxadiazine-2,4,6(3H,5H)-trione is used as an antibacterial agent due to its potential to inhibit the growth of certain bacteria. Its effectiveness in this application is under investigation, and it may contribute to the development of new antibiotics to combat resistant strains.
Used in Antifungal Applications:
Similarly, 2H-1,3,5-Oxadiazine-2,4,6(3H,5H)-trione is explored for its antifungal properties, making it a candidate for use in antifungal treatments. Its ability to combat fungal infections could lead to new therapeutic options in the management of various fungal diseases.
Used in Medicinal Chemistry:
2H-1,3,5-Oxadiazine-2,4,6(3H,5H)-trione is applied in medicinal chemistry as a structural component in the design of new drugs. Its unique ring system can be modified to enhance the pharmacological properties of drug candidates, potentially leading to more effective and safer medications.

Check Digit Verification of cas no

The CAS Registry Mumber 6498-11-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,9 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6498-11:
(6*6)+(5*4)+(4*9)+(3*8)+(2*1)+(1*1)=119
119 % 10 = 9
So 6498-11-9 is a valid CAS Registry Number.

6498-11-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3,5-oxadiazinane-2,4,6-trione

1.2 Other means of identification

Product number -
Other names 2,4,6-Trioxo-tetrahydro-1.3.5-oxadiazin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6498-11-9 SDS

6498-11-9Downstream Products

6498-11-9Relevant academic research and scientific papers

Reactions of Carbonyl Diisocyanate with Amides and Acids

Akteries, Bernhard,Jochims, Johannes C.

, p. 669 - 682 (2007/10/02)

Carbonyl diisocyanate (1) reacts with primary amides to give 1-acylated isocyanuric acids (5, 6).With secondary amides, 1 affords the rather instable oxadiazinediones 4, which for certain substituents rearrange to give triazines (5, 10).With nucleophiles, compounds 4 give oligourets, e.g. with ureas pentaurets (11, 12) were obtained.Carbonyl diisocyanate reacts with hydrogen halides to afford the crystalline urea-1,3-dicarbonyl halides 13a-c.Diverse products (16, 17, 24, 26) were obtained with carboxylic acids.In most cases oxadiazinediones (26) were isolated, which can be transformed with nucleophiles into acyl ureas 30, 31, biurets 32, and triurets 33.Acetylation of 26 leads to the reactive heterocycles 34.

Carbonyl Diisocyanate: A New Preparation and Some Reactions

Akteries, Bernhard,Jochims, Johannes C.

, p. 83 - 95 (2007/10/02)

A preparation of carbonyl diisocyanate (2) from tri-n-butyltin isocyanate (4) and phosgene is reported.Correspondingly, the acyl isocyanates 6 were obtained from 4 with acyl chlorides.On standing, carbonyl diisocyanate trimerizes reversibly to the triazine 9, which could also be prepared by independent syntheses from the triazines 3 or 12.Reported are reactions of carbonyl diisocyanate with water, hydrogen sulfide, alcohols, phenol, phenol + carbodiimides, thiols, amines, primary ammonium salts, and N-unsubstituted imines leading to compounds 14-24.

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