64982-81-6

Basic information

• Product Name: trans-1,2,10,11-tetramethoxy-6-methyl-5,6,7,8-tetrahydrodibenzazecine
• CAS NO: 64982-81-6
• Molecular Weight: 369.461
• Mol File: 64982-81-6.mol

Chemical Properties

• CAS DataBase Reference: trans-1,2,10,11-tetramethoxy-6-methyl-5,6,7,8-tetrahydrodibenzazecine(CAS DataBase Reference)
• NIST Chemistry Reference: trans-1,2,10,11-tetramethoxy-6-methyl-5,6,7,8-tetrahydrodibenzazecine(64982-81-6)
• EPA Substance Registry System: trans-1,2,10,11-tetramethoxy-6-methyl-5,6,7,8-tetrahydrodibenzazecine(64982-81-6)

Safety Data

• Hazardous Substances Data: 64982-81-6(Hazardous Substances Data)

Upstream product

• 64982-77-0 2,3,11,12-Tetramethoxy-7-methyl-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinolinium; chloride 

Downstream Products

• 14028-91-2 (+/-)-alpinigenine 
• 14028-91-2 (+/-)-cis-alpinigenine 
• 65022-58-4 N-(2-formyl-3,4-dimethoxybenzyl)-N-(2-formyl-4,5-dimethoxyphenethyl)methylamine 

Relevant articles and documents

Total Synthesis of the Alkaloids (+/-)-Alpinigenine and (+/-)-cis-Alpinigenine

A stereoselective synthesis of the rhoeadine alkaloid (+/-)-cis-alpinigenine is described.Hofmann elimination of the known tetracyclic base (4) gave the trans-azecine (7) which afforded the diol (13) on oxidation with N-bromosuccinimide.Periodic acid cleavage of (13) yielded the dibenzaldehyde (14), which on photolysis resulted in the formation of (+/-)-cis-alpinigenine (20-30percent) and (+/-)-alpinigenine (1percent) involving endo (16) and exo (15) (4s+2s) intramolecular additions respectively of the intermediate photodienol-E (Scheme 1).