65000-12-6

Basic information

• Product Name: 2-Bromo-N,N-diethylbenzenesulphonamide
• Synonyms: 2-Bromo-N,N-diethylbenzenesulphonamide;2-Bromo-N,N-diethylbenzenesulfonamide;N,N-Diethyl 2-bromobenzenesulfonamide
• CAS NO: 65000-12-6
• Molecular Formula: C₁₀H₁₄BrNO₂S
• Molecular Weight: 292.2
• Product Categories: blocks;Bromides;Sulfonamides
• Mol File: 65000-12-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 76-78 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
• Boiling Point: 365.4 °C at 760 mmHg
• Flash Point: 174.8 °C
• Appearance: /
• Density: 1.431 g/cm³
• Vapor Pressure: 1.57E-05mmHg at 25°C
• Refractive Index: 1.556
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -5.61±0.70(Predicted)
• CAS DataBase Reference: 2-Bromo-N,N-diethylbenzenesulphonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-N,N-diethylbenzenesulphonamide(65000-12-6)
• EPA Substance Registry System: 2-Bromo-N,N-diethylbenzenesulphonamide(65000-12-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 65000-12-6(Hazardous Substances Data)

Usage

General Description

2-Bromo-N,N-diethylbenzenesulphonamide is a chemical compound that belongs to the category of organic compounds known as benzenesulfonyl compounds. Its molecular formula is C10H14BrNO2S. Specifics about its properties such as its density, boiling point, melting point, etc., may vary based on conditions. As the name suggests, this chemical consists of a benzene ring bonded to a sulfonyl group, with a bromine atom and a diethylamine functional group attached. While it has potential applications in various fields due to its chemical reactivity, specific uses are dependent on the context. The compound must be handled appropriately to ensure safety, like any other chemical.

InChI:InChI=1/C10H14BrNO2S/c1-3-12(4-2)15(13,14)10-8-6-5-7-9(10)11/h5-8H,3-4H2,1-2H3

Upstream product

• 615-36-1 2-bromoaniline 
• 2905-25-1 o-bromobenzenesulfonyl chloride 
• 60199-33-9 ortho-bromobenzenesulfonyl hydrazide 
• 121-44-8 triethylamine 
• 1319750-41-8 1-(2-bromophenyl)-3,3-diethyltriaz-1-ene 
• 109-89-7 diethylamine 
• 108-86-1 bromobenzene 

Downstream Products

• 65000-18-2 N-ethyl-N-vinylbenzenesulfonamide 

Relevant articles and documents

An approach to C-N activation: Coupling of arenesulfonyl hydrazides and arenesulfonyl chlorides with: Tert -amines via a metal-, oxidant- and halogen-free anodic oxidation

tert-Amines were harnessed to afford arenesulfonyl hydrazides and arenesulfonyl chlorides via a metal-, oxidant- and halogen-free electrochemical oxidative coupling in an undivided cell at RT. This environmentally benign approach afforded a wide spectrum of sulfonamides in satisfactory yields using cheap and renewable Pencil Graphite Electrodes (PGEs).

Synthesis of sulfonamides: Via copper-catalyzed oxidative C-N bond cleavage of tertiary amines

A copper-catalyzed coupling reaction of sulfonyl chlorides with tertiary amines via the oxidative C-N bond cleavage of tertiary amines was developed. Sulfonamides were synthesized using this strategy in moderate to good yields. The reaction was applicable to various tertiary amines, as well as sulfonyl chlorides.

Palladium-catalysed dehydrogenative sp3 C-H bonds functionalisation into alkenes: A direct access to N-alkenylbenzenesulfonamides

The palladium-catalysed dehydrogenation of sp3 carbon-hydrogen bonds of N-alkylbenzenesulfonamides allows a simple access to N-alkenylbenzenesulfonamides. The reaction proceeds with easily accessible catalysts, with pivalate as a base, and allo