65016-19-5Relevant academic research and scientific papers
NHC-catalyzed Truce-Smiles rearrangement of: N -aryl methacrylamides for the synthesis of trans -cinnamides
Hu, Yuanyuan,Wang, Zhen,Luo, Honggen,Jin, Hongwei,Liu, Yunkui,Zhou, Bingwei
supporting information, p. 3834 - 3837 (2021/05/14)
Herein we describe a NHC-catalyzed Truce-Smiles rearrangement of N-aryl methacrylamides which enables the cleavage of an inert aryl C-N bond. A range of trans-cinnamides could be obtained by the direct construction of a C(aryl)-C(alkenyl) bond and functional groups such as Br, Cl, CN, and pyridinyl are compatible with NHC catalysis. The reaction features high atom-economy, transition-metal free catalysis, and easily available substrates. This journal is
Direct Csp3-H methylenation of 2-arylacetamides using DMF/Me2NH-BH3 as the methylene source
Liu, Yuting,Wang, Chang-Ling,Xia, Hui-Min,Wang, Zhijuan,Wang, Yi-Feng
supporting information, p. 6153 - 6157 (2019/07/03)
A direct Csp3-H methylenation of 2-arylacetamides using DMF/Me2NH-BH3 as the methylene source was developed. The formyl group of DMF delivered the carbon and one hydrogen atoms, and the Me2NH-BH3 dona
Palladium(II)-catalyzed regioselective carbonylative coupling of aniline derivatives with terminal aryl acetylenes to give acrylamides under syngas conditions
El Ali,El-Ghanam,Fettouhi,Tijani
, p. 5761 - 5764 (2007/10/03)
The carbonylative coupling of aniline derivatives (1a-h) with terminal aryl acetylenes (2a, b) catalyzed by Pd(OAc)2 and 1,4- bis(diphenylphosphino)butane (dppb) under syngas conditions affords acrylamide derivatives 3 or 3' in excellent yields
