65017-39-2

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 8-Methyl-
• Synonyms: 4H-1-Benzopyran-4-one, 8-Methyl-;8-methyl-4H-chromen-4-one
• CAS NO: 65017-39-2
• Molecular Formula: C₁₀H₈O₂
• Molecular Weight: 160.16932
• Mol File: 65017-39-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 8-Methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 8-Methyl-(65017-39-2)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 8-Methyl-(65017-39-2)

Safety Data

• Hazardous Substances Data: 65017-39-2(Hazardous Substances Data)

Upstream product

• 70695-71-5 3-bromo-8-methyl-chroman-4-one 
• 699-91-2 2-acetyl-6-methylphenol 
• 109-94-4 formic acid ethyl ester 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 25173-35-7 3-(2-methylphenoxy)propanoic acid 
• 49660-56-2 8-methylchroman-4-one 

Downstream Products

• 65061-44-1 8-methylchromone phenylhydrazone 
• 65017-41-6 1-phenyl-5-(2'-hydroxy-3'-methylphenyl)-pyrazole 
• 74575-09-0 2-hydroxy-3-methyl-ω-formylacetophenone bisphenylhydrazone 
• 123532-20-7 3-(2-hydroxy-3-methylphenyl)-1-methylpyrazole 
• 123532-24-1 5-(2-hydroxy-3-methylphenyl)-1-methylpyrazole 
• 123532-16-1 N₁-2-(2-hydroxy-3-methylbenzoyl)vinyl-N₁-methylhydrazine 
• 164171-57-7 5-(2-hydroxy-3-methylphenyl)isoxazole 
• 331683-40-0 5-bromo-8-methyl-4H-benzopyran-4-one 
• 74575-08-9 1-phenyl-5-(2'-methoxy-3'-methylphenyl)-pyrazole 
• 74575-07-8 1-phenyl-5-(2'-benzoyloxy-3'-methylphenyl)-pyrazole 
• 74575-10-3 8-methylchromone N-benzoylphenylhydrazone 

Relevant articles and documents

Ruthenium(II)-Catalyzed C-H Activation of Chromones with Maleimides to Synthesize Succinimide/Maleimide-Containing Chromones

An efficient route for the coupling of maleimides with chromones at the C5-position has been developed under Ru(II) catalysis. It could provide 1,4-addition products and oxidative Heck-type products by switching additives. Benzoic acid led to the formation of 1,4-addition products under solvent-free conditions, and silver acetate was promoted to the generation of oxidative Heck-type products. Various maleimides and chromones were suitable for this transformation, affording the desired products with good to excellent yields in a short reaction time. To understand the mechanism of this reaction, deuteration studies and control experiments have been performed.

Substituent-Oriented Synthesis of Substituted Pyrazoles/Chromeno[3,2- c]pyrazoles via Sequential Reactions of Chromones/3-Chlorochromones and Tosylhydrazones

A facile and efficient synthetic strategy for the chemoselective synthesis of monocyclic/tricyclic-fused pyrazoles was developed, and it was oriented by different 3-position substituents (H or Cl) on the chromones. The reaction proceeded in a one-pot sequential way with a broad substrate scope and moderate to excellent yields.