6502-20-1Relevant articles and documents
rabbit ear oxaldehyde a method of production
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Paragraph 0020; 0021, (2016/10/10)
The invention relates to a cyclamen aldehyde production method. The method concretely comprises the following steps: mixing methylacrolein dipropionic acid with isopropyl benzene, slowly adding a titanium tetrachloride and trifluoromethanesulfonic acid mixed solution in a dropwise manner at a low temperature while stirring, reacting, slowly pouring a diluted hydrochloric acid solution into the above obtained reaction solution after completing the reaction, hydrolyzing, taking the obtained organic phase, adding sodium hydroxide and methanol, carrying out a de-esterification reaction, washing by using water after completing the de-esterification reaction, separating the obtained organic layer, and rectifying the above obtained crude product to obtain highly pure cyclamen aldehyde. An innovative titanium tetrachloride and catalytic amount trifluoromethanesulfonic acid double-acid catalysis mode is adopted, the concrete dropwise addition sequence, the reaction time and the temperature are limited, so side reactions are reduced, and the purity of the cyclamen aldehyde is improved; and isopropyl benzene is cheap and easily available, and can be simultaneously used as a solvent and a reactant without adding other solvents, so the method disclosed in the invention has great advantages in cost and three-waste control.
An efficient TiCl4-catalysed method for the synthesis of para-substituted aromatic aldehydes
Zhou, Chenfeng,Su, Weike
, p. 555 - 557 (2015/11/27)
An efficient and highly selective synthesis of para-substituted aromatic aldehydes has been achieved by TiCl4-catalysed Friedel-Crafts alkylation of monosubstituted benzenes with methacrolein diacetyl acetal.
Oxidative coupling of benzenes with α,β-unsaturated aldehydes by the Pd(OAc)2/molybdovanadophosphoric acid/O2 system
Yamada, Tomoyuki,Sakaguchi, Satoshi,Ishii, Yasutaka
, p. 5471 - 5474 (2008/04/18)
The oxidative coupling reaction of benzene with an α,β- unsaturated aldehyde was examined by the combined catalytic system of Pd(OAc)2 with molybdovanadophosphoric acid (HPMoV) under atmospheric dioxygen. Thus, the reaction of benzene with acrolein under dioxygen (1 atm) by the use of catalytic amounts of Pd(OAc)2 and H4PMo 11VO40·26H2O in the presence of dibenzoylmethane as a ligand in propionic acid at 90 °C for 1.5 h afforded cinnamaldehyde in 59% yield and β-phenylcinnamaldehyde in 5% yield. This catalytic system was extended to the direct oxidative coupling through the C-H bond activation of various arenes with acrolein and methacrolein.
HYDROGENATION OF 3-(4-ISOPROPYLPHENYL)-2-METHYL-2-PROPENAL TO YIELD 3-(4-ISOPROPYLPHENYL)-2-METHYLPROPANAL ON PALLADIUM CATALYST
Pak, A. M.,Ginzburg, M. A.,Turganbaeva, S. M.,Gabdrakipov, V. Z.,Kartonozhkina, O. I.,et al.
, p. 1040 - 1043 (2007/10/02)
A study is carried out on the hydrogenation of 3-(4-isopropylphenyl)-2-methyl-2-propenal to yield 3-(4-isopropylphenyl)-2-methylpropanal on Pd/Al2O3 catalysts with various amounts of palladium in ethanol in the pressure range from 1 to 100 atm.We determined conditions for the selective hydrogenation of the ethylenic bond conjugated with the carboxylic group; the selectivity was 96-98percent.
